Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006949095> ?p ?o ?g. }
- W2006949095 endingPage "2920" @default.
- W2006949095 startingPage "2913" @default.
- W2006949095 abstract "Abstract To elucidate the protein–protein interactions of hemoglobin (Hb) variants A and A 2 , HbA was first shown to bind with HbA 2 in live red blood cells (RBCs) by diagonal electrophoresis and then the interaction between HbA and HbA 2 outside the RBC was shown by cross electrophoresis. The starch–agarose gel electrophoresis of hemolysate, RBCs, freeze‐thawed RBCs and the supernatant of freeze‐thawed RBCs showed that the interaction between HbA and HbA 2 was affected by membrane integrity. To identify the proteins involved in the interaction, protein components located between HbA and HbA 2 in RBCs (RBC HbA‐HbA 2 ) and hemolysate (hemolysate HbA‐HbA 2 ) were isolated from the starch–agarose gel and separated by 5–12% SDS‐PAGE. The results showed that there was a ≈22 kDa protein band located in the RBC HbA‐HbA 2 but not in hemolysate HbA‐HbA 2 . Sequencing by LC/MS/MS showed that this band was a protein complex that included mainly thioredoxin peroxidase B, α‐globin, δ‐globin and β‐globin. Thus, using our unique in vivo whole blood cell electrophoresis release test, Hbs were proven for the first time to interact with other proteins in the live RBC." @default.
- W2006949095 created "2016-06-24" @default.
- W2006949095 creator A5009007337 @default.
- W2006949095 creator A5012364401 @default.
- W2006949095 creator A5016391084 @default.
- W2006949095 creator A5019801578 @default.
- W2006949095 creator A5040005368 @default.
- W2006949095 creator A5060851233 @default.
- W2006949095 creator A5073831032 @default.
- W2006949095 date "2010-08-02" @default.
- W2006949095 modified "2023-10-16" @default.
- W2006949095 title "Interactions of hemoglobin in live red blood cells measured by the electrophoresis release test" @default.
- W2006949095 cites W1598543580 @default.
- W2006949095 cites W1987604884 @default.
- W2006949095 cites W1999382188 @default.
- W2006949095 cites W2003690880 @default.
- W2006949095 cites W2004209427 @default.
- W2006949095 cites W2011251621 @default.
- W2006949095 cites W2016894199 @default.
- W2006949095 cites W2019852916 @default.
- W2006949095 cites W2027666746 @default.
- W2006949095 cites W2047110122 @default.
- W2006949095 cites W2051230054 @default.
- W2006949095 cites W2051687003 @default.
- W2006949095 cites W2087843286 @default.
- W2006949095 cites W2088437224 @default.
- W2006949095 cites W2095357177 @default.
- W2006949095 cites W2098048169 @default.
- W2006949095 cites W2098143583 @default.
- W2006949095 cites W2099002535 @default.
- W2006949095 cites W2104447833 @default.
- W2006949095 cites W2121470019 @default.
- W2006949095 cites W2152771944 @default.
- W2006949095 cites W2156583650 @default.
- W2006949095 cites W2158496331 @default.
- W2006949095 cites W2244043776 @default.
- W2006949095 cites W2521617650 @default.
- W2006949095 doi "https://doi.org/10.1002/elps.201000034" @default.
- W2006949095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20680969" @default.
- W2006949095 hasPublicationYear "2010" @default.
- W2006949095 type Work @default.
- W2006949095 sameAs 2006949095 @default.
- W2006949095 citedByCount "6" @default.
- W2006949095 countsByYear W20069490952012 @default.
- W2006949095 countsByYear W20069490952013 @default.
- W2006949095 countsByYear W20069490952015 @default.
- W2006949095 countsByYear W20069490952016 @default.
- W2006949095 crossrefType "journal-article" @default.
- W2006949095 hasAuthorship W2006949095A5009007337 @default.
- W2006949095 hasAuthorship W2006949095A5012364401 @default.
- W2006949095 hasAuthorship W2006949095A5016391084 @default.
- W2006949095 hasAuthorship W2006949095A5019801578 @default.
- W2006949095 hasAuthorship W2006949095A5040005368 @default.
- W2006949095 hasAuthorship W2006949095A5060851233 @default.
- W2006949095 hasAuthorship W2006949095A5073831032 @default.
- W2006949095 hasConcept C116084860 @default.
- W2006949095 hasConcept C125996951 @default.
- W2006949095 hasConcept C144647389 @default.
- W2006949095 hasConcept C153911025 @default.
- W2006949095 hasConcept C185592680 @default.
- W2006949095 hasConcept C2776557347 @default.
- W2006949095 hasConcept C2776589458 @default.
- W2006949095 hasConcept C2778271344 @default.
- W2006949095 hasConcept C2778476535 @default.
- W2006949095 hasConcept C2778917026 @default.
- W2006949095 hasConcept C41625074 @default.
- W2006949095 hasConcept C43617362 @default.
- W2006949095 hasConcept C552990157 @default.
- W2006949095 hasConcept C55493867 @default.
- W2006949095 hasConcept C86803240 @default.
- W2006949095 hasConceptScore W2006949095C116084860 @default.
- W2006949095 hasConceptScore W2006949095C125996951 @default.
- W2006949095 hasConceptScore W2006949095C144647389 @default.
- W2006949095 hasConceptScore W2006949095C153911025 @default.
- W2006949095 hasConceptScore W2006949095C185592680 @default.
- W2006949095 hasConceptScore W2006949095C2776557347 @default.
- W2006949095 hasConceptScore W2006949095C2776589458 @default.
- W2006949095 hasConceptScore W2006949095C2778271344 @default.
- W2006949095 hasConceptScore W2006949095C2778476535 @default.
- W2006949095 hasConceptScore W2006949095C2778917026 @default.
- W2006949095 hasConceptScore W2006949095C41625074 @default.
- W2006949095 hasConceptScore W2006949095C43617362 @default.
- W2006949095 hasConceptScore W2006949095C552990157 @default.
- W2006949095 hasConceptScore W2006949095C55493867 @default.
- W2006949095 hasConceptScore W2006949095C86803240 @default.
- W2006949095 hasIssue "17" @default.
- W2006949095 hasLocation W20069490951 @default.
- W2006949095 hasLocation W20069490952 @default.
- W2006949095 hasOpenAccess W2006949095 @default.
- W2006949095 hasPrimaryLocation W20069490951 @default.
- W2006949095 hasRelatedWork W1983882710 @default.
- W2006949095 hasRelatedWork W2014718210 @default.
- W2006949095 hasRelatedWork W2041044489 @default.
- W2006949095 hasRelatedWork W2074201774 @default.
- W2006949095 hasRelatedWork W2352571116 @default.
- W2006949095 hasRelatedWork W2353115207 @default.
- W2006949095 hasRelatedWork W2382319681 @default.
- W2006949095 hasRelatedWork W2476713926 @default.