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- W2006957229 abstract "We studied the effects of switching antipsychotic drug-treated patients with schizophrenia or bipolar disorder who evidenced adverse metabolic side effects as indicated by a triglyceride/high-density lipoprotein ratio (TG/HDL) ≥ 3.5 to aripiprazole (ARIP; 5-30 mg/day, n = 24) or ziprasidone (ZIP; 40-160 mg/day, n = 28). Anthropometric and metabolic measures, psychopathology, quality of life and motor adverse effects were assessed over a 52-week period with evaluations at baseline, 6, 12, 26 and 52 weeks. There were statistically significant improvements in body weight, body mass index (BMI), TG, HDL and TG/HDL which did not differ between treatments. However, numerous secondary measures including weight and BMI, and the proportion of patients who lost ≥ 7% or who no longer met criteria for obesity, favored ZIP over ARIP. Decreases in total cholesterol and increases in HDL-cholesterol also favored ZIP. On the other hand, decreases in TG/HDL ratio and reduction in HgbA1c favored ARIP. There were no significant time or group × time interaction effects for most psychopathology measures; however, Global Assessment of Functioning Scores favored ARIP at 6 and 12 months. We conclude that switching patients with evidence of metabolic side effects to either ARIP or ZIP may be beneficial for some, but not all metabolic measures, with minimal risk of worsening of psychopathology and possibly some benefit in that regard as well." @default.
- W2006957229 created "2016-06-24" @default.
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- W2006957229 date "2012-01-09" @default.
- W2006957229 modified "2023-09-30" @default.
- W2006957229 title "Comparative effectiveness of switching antipsychotic drug treatment to aripiprazole or ziprasidone for improving metabolic profile and atherogenic dyslipidemia: a 12-month, prospective, open-label study" @default.
- W2006957229 cites W1482094277 @default.
- W2006957229 cites W1963544666 @default.
- W2006957229 cites W1964134628 @default.
- W2006957229 cites W1969303234 @default.
- W2006957229 cites W1971287303 @default.
- W2006957229 cites W1973807164 @default.
- W2006957229 cites W1973927961 @default.
- W2006957229 cites W1974541005 @default.
- W2006957229 cites W1975800742 @default.
- W2006957229 cites W1976303732 @default.
- W2006957229 cites W1978727000 @default.
- W2006957229 cites W1979352055 @default.
- W2006957229 cites W1979797229 @default.
- W2006957229 cites W198190726 @default.
- W2006957229 cites W1992181956 @default.
- W2006957229 cites W1993446055 @default.
- W2006957229 cites W1994877202 @default.
- W2006957229 cites W2002701207 @default.
- W2006957229 cites W2006647811 @default.
- W2006957229 cites W2013102015 @default.
- W2006957229 cites W2017969492 @default.
- W2006957229 cites W2018689362 @default.
- W2006957229 cites W2023570724 @default.
- W2006957229 cites W2025635941 @default.
- W2006957229 cites W2031094750 @default.
- W2006957229 cites W2035765606 @default.
- W2006957229 cites W2036358842 @default.
- W2006957229 cites W2037977025 @default.
- W2006957229 cites W2042217399 @default.
- W2006957229 cites W2053972943 @default.
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- W2006957229 cites W2062359581 @default.
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- W2006957229 cites W2073712495 @default.
- W2006957229 cites W2077247955 @default.
- W2006957229 cites W2077518307 @default.
- W2006957229 cites W2078621701 @default.
- W2006957229 cites W2079567719 @default.
- W2006957229 cites W2086748382 @default.
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- W2006957229 cites W2153834445 @default.
- W2006957229 cites W2160720439 @default.
- W2006957229 cites W2162961854 @default.
- W2006957229 cites W2170562380 @default.
- W2006957229 cites W4240735590 @default.
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- W2006957229 doi "https://doi.org/10.1177/0269881111430748" @default.
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