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- W2006982783 abstract "Geringfügig überlegen ist Epothilon B 1 (R = Me) gegenüber Paclitaxel (Taxol) im Hinblick auf die Antitumoraktivität. Dies geht aus In‐vivo‐Untersuchungen mit Tumormodellen in der Maus hervor. Sehr empfindlich gegenüber Strukturänderungen ist bei den Epothilonen der „Acylsektor”︁ C1C8. Die anderen beiden Sektoren (siehe rechts) können in Grenzen variiert werden, allerdings wurde dabei bisher noch keine deutlich antitumoraktivere Verbindung identifiziert. magnified image" @default.
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- W2006982783 date "1997-10-02" @default.
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- W2006982783 title "Struktur‐Wirkungs‐Beziehungen der Epothilone und erster In‐vivo‐Vergleich mit Paclitaxel" @default.
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- W2006982783 doi "https://doi.org/10.1002/ange.19971091916" @default.
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