FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006991610> ?p ?o ?g. }

• W2006991610 abstract "To further study the role of arachidonic acid metabolites in the development of hyperoxic lung injury and the function of PMNs and/or alveolar macrophages in facilitating this role, we exposed adult rabbits to greater than 95% O2 or air for 24, 40, 48, or 65 hours. At the end of each study, bronchoalveolar lavage [BAL] of the left lung was performed, and the right lung was inflated and fixed for light and electron microscopy. PGE2, 6-keto-PGF1 alpha and thromboxane B2 were measured by RIA in arterial and venous plasma at the beginning and end of each study and in BAL fluid obtained at sacrifice. Production of these three PGs by BAL cells placed in cell culture was also measured. Significant hyperoxic lung injury did not develop until 65 hours, as evidenced by significant increase in BAL total protein and percent PMNs, and by morphologic findings. At 40 hours, however, BAL fluid PGE2 and 6-keto-PGF1 alpha increased and BAL cell production of all 3 PGs was significantly increased (p less than .05). In summary, the early PG increases observed in these studies may directly contribute to the development of hyperoxic lung injury or, rather, may be representative of a generalized increase in all arachidonic acid metabolites, including the lipoxygenase pathway. The increase in BAL cell PG production and increased PG concentrations in BAL fluid prior to any increase in BAL PMNs suggest that the AM may be the source of the early arachidonic acid metabolite increase in response to hyperoxia." @default.
• W2006991610 created "2016-06-24" @default.
• W2006991610 creator A5004614528 @default.
• W2006991610 creator A5008810823 @default.
• W2006991610 creator A5009662174 @default.
• W2006991610 creator A5035909098 @default.
• W2006991610 creator A5040561505 @default.
• W2006991610 creator A5041302124 @default.
• W2006991610 creator A5070437703 @default.
• W2006991610 date "1986-12-01" @default.
• W2006991610 modified "2023-09-24" @default.
• W2006991610 title "The early involvement of pulmonary prostaglandins in hyperoxic lung injury" @default.
• W2006991610 cites W1728480991 @default.
• W2006991610 cites W1740633437 @default.
• W2006991610 cites W1897118390 @default.
• W2006991610 cites W1964060503 @default.
• W2006991610 cites W1983377205 @default.
• W2006991610 cites W1988508911 @default.
• W2006991610 cites W2021222953 @default.
• W2006991610 cites W2022409957 @default.
• W2006991610 cites W2028049707 @default.
• W2006991610 cites W2033874478 @default.
• W2006991610 cites W2043952767 @default.
• W2006991610 cites W2047531536 @default.
• W2006991610 cites W2061663169 @default.
• W2006991610 cites W2063371918 @default.
• W2006991610 cites W2069870207 @default.
• W2006991610 cites W2084792257 @default.
• W2006991610 cites W2107192875 @default.
• W2006991610 cites W2229750475 @default.
• W2006991610 cites W2236605420 @default.
• W2006991610 cites W2342764320 @default.
• W2006991610 cites W2409917330 @default.
• W2006991610 cites W2594294830 @default.
• W2006991610 doi "https://doi.org/10.1016/0262-1746(86)90058-2" @default.
• W2006991610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3103136" @default.
• W2006991610 hasPublicationYear "1986" @default.
• W2006991610 type Work @default.
• W2006991610 sameAs 2006991610 @default.
• W2006991610 citedByCount "14" @default.
• W2006991610 crossrefType "journal-article" @default.
• W2006991610 hasAuthorship W2006991610A5004614528 @default.
• W2006991610 hasAuthorship W2006991610A5008810823 @default.
• W2006991610 hasAuthorship W2006991610A5009662174 @default.
• W2006991610 hasAuthorship W2006991610A5035909098 @default.
• W2006991610 hasAuthorship W2006991610A5040561505 @default.
• W2006991610 hasAuthorship W2006991610A5041302124 @default.
• W2006991610 hasAuthorship W2006991610A5070437703 @default.
• W2006991610 hasConcept C126322002 @default.
• W2006991610 hasConcept C134018914 @default.
• W2006991610 hasConcept C142724271 @default.
• W2006991610 hasConcept C16685009 @default.
• W2006991610 hasConcept C181199279 @default.
• W2006991610 hasConcept C185592680 @default.
• W2006991610 hasConcept C203014093 @default.
• W2006991610 hasConcept C2776785769 @default.
• W2006991610 hasConcept C2777477808 @default.
• W2006991610 hasConcept C2777714996 @default.
• W2006991610 hasConcept C2777961210 @default.
• W2006991610 hasConcept C2778078955 @default.
• W2006991610 hasConcept C2780664492 @default.
• W2006991610 hasConcept C2780672939 @default.
• W2006991610 hasConcept C2781080829 @default.
• W2006991610 hasConcept C55493867 @default.
• W2006991610 hasConcept C71924100 @default.
• W2006991610 hasConcept C89560881 @default.
• W2006991610 hasConceptScore W2006991610C126322002 @default.
• W2006991610 hasConceptScore W2006991610C134018914 @default.
• W2006991610 hasConceptScore W2006991610C142724271 @default.
• W2006991610 hasConceptScore W2006991610C16685009 @default.
• W2006991610 hasConceptScore W2006991610C181199279 @default.
• W2006991610 hasConceptScore W2006991610C185592680 @default.
• W2006991610 hasConceptScore W2006991610C203014093 @default.
• W2006991610 hasConceptScore W2006991610C2776785769 @default.
• W2006991610 hasConceptScore W2006991610C2777477808 @default.
• W2006991610 hasConceptScore W2006991610C2777714996 @default.
• W2006991610 hasConceptScore W2006991610C2777961210 @default.
• W2006991610 hasConceptScore W2006991610C2778078955 @default.
• W2006991610 hasConceptScore W2006991610C2780664492 @default.
• W2006991610 hasConceptScore W2006991610C2780672939 @default.
• W2006991610 hasConceptScore W2006991610C2781080829 @default.
• W2006991610 hasConceptScore W2006991610C55493867 @default.
• W2006991610 hasConceptScore W2006991610C71924100 @default.
• W2006991610 hasConceptScore W2006991610C89560881 @default.
• W2006991610 hasLocation W20069916101 @default.
• W2006991610 hasLocation W20069916102 @default.
• W2006991610 hasOpenAccess W2006991610 @default.
• W2006991610 hasPrimaryLocation W20069916101 @default.
• W2006991610 hasRelatedWork W185893713 @default.
• W2006991610 hasRelatedWork W1964479567 @default.
• W2006991610 hasRelatedWork W1987100741 @default.
• W2006991610 hasRelatedWork W1989654322 @default.
• W2006991610 hasRelatedWork W2006991610 @default.
• W2006991610 hasRelatedWork W2023027368 @default.
• W2006991610 hasRelatedWork W2090784682 @default.
• W2006991610 hasRelatedWork W2268126300 @default.
• W2006991610 hasRelatedWork W2410608214 @default.
• W2006991610 hasRelatedWork W2416360926 @default.
• W2006991610 isParatext "false" @default.
• W2006991610 isRetracted "false" @default.

• next