Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007003003> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2007003003 abstract "We conducted this prospective randomized trial of intravenous immunoglobulin (IVIG) treatment in children with newly diagnosed immune thrombocytopenic purpura (ITP) to compare the efficacy of IVIG to standard and higher doses of anti-D IVIG. Seventy-eight patients who were previously untreated and between the age of 1 and 18 years with newly diagnosed acute ITP and a platelet concentration less than 20×10/l were eligible for enrollment. In this study IVIG treatment was compared with two different doses of anti-D. Study patients were randomized to receive treatment according to one of the two single anti-D IVIG doses [50 μg/kg (n=19) or 75 μg/kg (n=20)] or 2 g/kg (400 mg/kg per day, 5 day) total dose of IVIG (n=39). There is a significant increase of 24th hour, 48th hour, 72nd hour, 7th day and 30th day platelet counts in IVIG (2 g/kg, total dose) group compared to anti-D IVIG 50 μg/kg and anti-D IVIG 75 μg/kg groups. However, there were no difference between 24th hour, 48th hour, 72nd hour, 7th day and 30th day platelet counts across anti-D IVIG 50 μg/kg and anti-D IVIG 75 μg/kg groups. In conclusion, this study suggests that IVIG is well tolerated and significantly more effective than standard and high-dose anti-D IVIG for the treatment of newly diagnosed ITP in children. Apart from this, we believe that IVIG might be the first-line treatment of these patients. Regarding this issue further prospective studies comparing different IVIG treatment regimens with anti-D IVIG treatment regimens are needed." @default.
- W2007003003 created "2016-06-24" @default.
- W2007003003 creator A5012849397 @default.
- W2007003003 creator A5014602182 @default.
- W2007003003 creator A5032989001 @default.
- W2007003003 creator A5078366440 @default.
- W2007003003 creator A5079916945 @default.
- W2007003003 creator A5086646536 @default.
- W2007003003 date "2013-07-01" @default.
- W2007003003 modified "2023-10-12" @default.
- W2007003003 title "A comparison of intravenous immunoglobulin (2 g/kg totally) and single doses of anti-D immunoglobulin at 50 μg/kg, 75 μg/kg in newly diagnosed children with idiopathic thrombocytopenic purpura" @default.
- W2007003003 cites W1965115571 @default.
- W2007003003 cites W1994082251 @default.
- W2007003003 cites W2007735229 @default.
- W2007003003 cites W2020418503 @default.
- W2007003003 cites W2021383699 @default.
- W2007003003 cites W2057924704 @default.
- W2007003003 cites W2058437162 @default.
- W2007003003 cites W2060181808 @default.
- W2007003003 cites W2073339219 @default.
- W2007003003 cites W2095977542 @default.
- W2007003003 cites W2143342788 @default.
- W2007003003 doi "https://doi.org/10.1097/mbc.0b013e32835e5337" @default.
- W2007003003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23470649" @default.
- W2007003003 hasPublicationYear "2013" @default.
- W2007003003 type Work @default.
- W2007003003 sameAs 2007003003 @default.
- W2007003003 citedByCount "13" @default.
- W2007003003 countsByYear W20070030032013 @default.
- W2007003003 countsByYear W20070030032014 @default.
- W2007003003 countsByYear W20070030032015 @default.
- W2007003003 countsByYear W20070030032016 @default.
- W2007003003 countsByYear W20070030032017 @default.
- W2007003003 countsByYear W20070030032019 @default.
- W2007003003 countsByYear W20070030032020 @default.
- W2007003003 countsByYear W20070030032021 @default.
- W2007003003 crossrefType "journal-article" @default.
- W2007003003 hasAuthorship W2007003003A5012849397 @default.
- W2007003003 hasAuthorship W2007003003A5014602182 @default.
- W2007003003 hasAuthorship W2007003003A5032989001 @default.
- W2007003003 hasAuthorship W2007003003A5078366440 @default.
- W2007003003 hasAuthorship W2007003003A5079916945 @default.
- W2007003003 hasAuthorship W2007003003A5086646536 @default.
- W2007003003 hasConcept C126322002 @default.
- W2007003003 hasConcept C159654299 @default.
- W2007003003 hasConcept C168563851 @default.
- W2007003003 hasConcept C203014093 @default.
- W2007003003 hasConcept C2779771385 @default.
- W2007003003 hasConcept C71924100 @default.
- W2007003003 hasConcept C89560881 @default.
- W2007003003 hasConcept C90924648 @default.
- W2007003003 hasConceptScore W2007003003C126322002 @default.
- W2007003003 hasConceptScore W2007003003C159654299 @default.
- W2007003003 hasConceptScore W2007003003C168563851 @default.
- W2007003003 hasConceptScore W2007003003C203014093 @default.
- W2007003003 hasConceptScore W2007003003C2779771385 @default.
- W2007003003 hasConceptScore W2007003003C71924100 @default.
- W2007003003 hasConceptScore W2007003003C89560881 @default.
- W2007003003 hasConceptScore W2007003003C90924648 @default.
- W2007003003 hasLocation W20070030031 @default.
- W2007003003 hasLocation W20070030032 @default.
- W2007003003 hasOpenAccess W2007003003 @default.
- W2007003003 hasPrimaryLocation W20070030031 @default.
- W2007003003 hasRelatedWork W148413925 @default.
- W2007003003 hasRelatedWork W1991437102 @default.
- W2007003003 hasRelatedWork W2001971347 @default.
- W2007003003 hasRelatedWork W2002284795 @default.
- W2007003003 hasRelatedWork W2011447214 @default.
- W2007003003 hasRelatedWork W2013439593 @default.
- W2007003003 hasRelatedWork W2021853383 @default.
- W2007003003 hasRelatedWork W2038758203 @default.
- W2007003003 hasRelatedWork W2057924704 @default.
- W2007003003 hasRelatedWork W2059190713 @default.
- W2007003003 hasRelatedWork W2060181808 @default.
- W2007003003 hasRelatedWork W2060455513 @default.
- W2007003003 hasRelatedWork W2107638524 @default.
- W2007003003 hasRelatedWork W2163543567 @default.
- W2007003003 hasRelatedWork W2168866941 @default.
- W2007003003 hasRelatedWork W2273505208 @default.
- W2007003003 hasRelatedWork W2591088718 @default.
- W2007003003 hasRelatedWork W2592546469 @default.
- W2007003003 hasRelatedWork W3133213534 @default.
- W2007003003 hasRelatedWork W3180837064 @default.
- W2007003003 isParatext "false" @default.
- W2007003003 isRetracted "false" @default.
- W2007003003 magId "2007003003" @default.
- W2007003003 workType "article" @default.