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- W2007006871 endingPage "1038" @default.
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- W2007006871 abstract "Tolerogenic vaccines represent a new class of vaccine designed to re-establish immunological tolerance, restore immune homeostasis, and thereby reverse autoimmune disease. Tolerogenic vaccines induce long-term, antigen-specific, inhibitory memory that blocks pathogenic T cell responses via loss of effector T cells and gain of regulatory T cell function. Substantial advances have been realized in the generation of tolerogenic vaccines that inhibit experimental autoimmune encephalomyelitis in a preclinical setting, and these vaccines may be a prequel of the tolerogenic vaccines that may have therapeutic benefit in Multiple Sclerosis. The purpose here is to provide a snapshot of the current concepts and future prospects of tolerogenic vaccination for Multiple Sclerosis, along with the central challenges to clinical application." @default.
- W2007006871 created "2016-06-24" @default.
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- W2007006871 date "2013-05-14" @default.
- W2007006871 modified "2023-10-11" @default.
- W2007006871 title "Tolerogenic vaccines for Multiple Sclerosis" @default.
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- W2007006871 doi "https://doi.org/10.4161/hv.23685" @default.
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