FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007020139> ?p ?o ?g. }

• W2007020139 endingPage "140" @default.
• W2007020139 startingPage "133" @default.
• W2007020139 abstract "The effects of isoproterenol, a beta-adrenoceptor agonist, on the production of interleukin-1beta in the brain and on mechanical nociception were examined in rats. Intracerebroventricular (i.c.v.) injection of isoproterenol at the dose of 3 microg/rat markedly induced interleukin-1beta mRNA in the molecular layer of the hippocampus, medial preoptic area, paraventricular thalamic nucleus, paraventricular hypothalamic nucleus, ventromedial hypothalamic nucleus, dorsomedial hypothalamic nucleus and central gray 1 h after injection. In these regions, interleukin-1beta mRNA was expressed mainly in the glial cells. The thresholds to the mechanical stimulation to the hind paw were elevated by i.c.v. administration of isoproterenol (1 to 10 microg/rat). When isoproterenol was given at the dose of 3 microg/rat, the analgesic effect showed two peaks. The first peak was observed at 60 min after injection and the second was observed at 180 min. The second phase of analgesia was antagonized by coadministration of interleukin-1 receptor antagonist. These results suggest that isoproterenol produces an analgesic effect, at least in part, through the induction of interleukin-1beta expression in the brain." @default.
• W2007020139 created "2016-06-24" @default.
• W2007020139 creator A5008347102 @default.
• W2007020139 creator A5009753180 @default.
• W2007020139 creator A5029722966 @default.
• W2007020139 creator A5041951543 @default.
• W2007020139 creator A5068548685 @default.
• W2007020139 creator A5070407720 @default.
• W2007020139 creator A5074728818 @default.
• W2007020139 date "1997-09-01" @default.
• W2007020139 modified "2023-09-24" @default.
• W2007020139 title "Intracerebroventricular injection of isoproterenol produces its analgesic effect through interleukin-1β production" @default.
• W2007020139 cites W1963710801 @default.
• W2007020139 cites W1972411255 @default.
• W2007020139 cites W1974981667 @default.
• W2007020139 cites W2002704531 @default.
• W2007020139 cites W2003897692 @default.
• W2007020139 cites W2022592499 @default.
• W2007020139 cites W2028923330 @default.
• W2007020139 cites W2054685256 @default.
• W2007020139 cites W2055471006 @default.
• W2007020139 cites W2056514859 @default.
• W2007020139 cites W2080685344 @default.
• W2007020139 cites W2087139593 @default.
• W2007020139 cites W2087454739 @default.
• W2007020139 cites W2090135185 @default.
• W2007020139 cites W2090196236 @default.
• W2007020139 cites W2145890122 @default.
• W2007020139 cites W2156243671 @default.
• W2007020139 doi "https://doi.org/10.1016/s0014-2999(97)01196-5" @default.
• W2007020139 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9369341" @default.
• W2007020139 hasPublicationYear "1997" @default.
• W2007020139 type Work @default.
• W2007020139 sameAs 2007020139 @default.
• W2007020139 citedByCount "20" @default.
• W2007020139 countsByYear W20070201392012 @default.
• W2007020139 countsByYear W20070201392019 @default.
• W2007020139 countsByYear W20070201392020 @default.
• W2007020139 countsByYear W20070201392021 @default.
• W2007020139 crossrefType "journal-article" @default.
• W2007020139 hasAuthorship W2007020139A5008347102 @default.
• W2007020139 hasAuthorship W2007020139A5009753180 @default.
• W2007020139 hasAuthorship W2007020139A5029722966 @default.
• W2007020139 hasAuthorship W2007020139A5041951543 @default.
• W2007020139 hasAuthorship W2007020139A5068548685 @default.
• W2007020139 hasAuthorship W2007020139A5070407720 @default.
• W2007020139 hasAuthorship W2007020139A5074728818 @default.
• W2007020139 hasConcept C118552586 @default.
• W2007020139 hasConcept C126322002 @default.
• W2007020139 hasConcept C134018914 @default.
• W2007020139 hasConcept C15490471 @default.
• W2007020139 hasConcept C170493617 @default.
• W2007020139 hasConcept C185592680 @default.
• W2007020139 hasConcept C24998067 @default.
• W2007020139 hasConcept C2776046087 @default.
• W2007020139 hasConcept C2776885963 @default.
• W2007020139 hasConcept C2777003273 @default.
• W2007020139 hasConcept C2778122271 @default.
• W2007020139 hasConcept C2778938600 @default.
• W2007020139 hasConcept C2780723820 @default.
• W2007020139 hasConcept C2780820201 @default.
• W2007020139 hasConcept C71924100 @default.
• W2007020139 hasConcept C98274493 @default.
• W2007020139 hasConceptScore W2007020139C118552586 @default.
• W2007020139 hasConceptScore W2007020139C126322002 @default.
• W2007020139 hasConceptScore W2007020139C134018914 @default.
• W2007020139 hasConceptScore W2007020139C15490471 @default.
• W2007020139 hasConceptScore W2007020139C170493617 @default.
• W2007020139 hasConceptScore W2007020139C185592680 @default.
• W2007020139 hasConceptScore W2007020139C24998067 @default.
• W2007020139 hasConceptScore W2007020139C2776046087 @default.
• W2007020139 hasConceptScore W2007020139C2776885963 @default.
• W2007020139 hasConceptScore W2007020139C2777003273 @default.
• W2007020139 hasConceptScore W2007020139C2778122271 @default.
• W2007020139 hasConceptScore W2007020139C2778938600 @default.
• W2007020139 hasConceptScore W2007020139C2780723820 @default.
• W2007020139 hasConceptScore W2007020139C2780820201 @default.
• W2007020139 hasConceptScore W2007020139C71924100 @default.
• W2007020139 hasConceptScore W2007020139C98274493 @default.
• W2007020139 hasFunder F4320309785 @default.
• W2007020139 hasFunder F4320320912 @default.
• W2007020139 hasIssue "2-3" @default.
• W2007020139 hasLocation W20070201391 @default.
• W2007020139 hasLocation W20070201392 @default.
• W2007020139 hasOpenAccess W2007020139 @default.
• W2007020139 hasPrimaryLocation W20070201391 @default.
• W2007020139 hasRelatedWork W1972357399 @default.
• W2007020139 hasRelatedWork W2034583712 @default.
• W2007020139 hasRelatedWork W2034768996 @default.
• W2007020139 hasRelatedWork W2051488242 @default.
• W2007020139 hasRelatedWork W2054992011 @default.
• W2007020139 hasRelatedWork W2064416809 @default.
• W2007020139 hasRelatedWork W2112726699 @default.
• W2007020139 hasRelatedWork W2414846389 @default.
• W2007020139 hasRelatedWork W2504779997 @default.
• W2007020139 hasRelatedWork W2773858965 @default.
• W2007020139 hasVolume "334" @default.
• W2007020139 isParatext "false" @default.

• next