Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007020183> ?p ?o ?g. }
- W2007020183 abstract "Capecitabine is an oral pro-drug of 5-fluorouracil (5FU) that has demonstrated an efficacy at least equivalent to standard leucovorin (LV)-modulated 5FU I.V. bolus regimen in the management of metastatic colorectal cancer (MCRC) patients as well as in the adjuvant setting. Despite a mild increase of some side effects, capecitabine is usually better tolerated than 5FU/LV, and could be preferable in the treatment of elderly patients. Moreover, usually the patients compliance with an oral treatment is better than with a regimen requiring the placement of a central venous catheter and infusional devices. The combination of capecitabine with oxaliplatin (XELOX regimen) was shown to be as effective as the combination of 5FU/LV with oxaliplatin (FOLFOX4 regimen) in MCRC. The XELOX regimen represents now a new standard of care for MCRC patients, and it will be probably considered in the next future an “user-friendly” alternative to the FOLFOX4 also in resected patients. The addition of bevacizumab to the XELOX regimen was demonstrated to further prolong the progression-free survival of metastatic patients, and is anticipated to reduce the risk of recurrence in resected colon cancer. Despite a higher acquisition cost than 5FU/LV, capecitabine is also cost-effective, because of the reduced costs for drug administration and management of adverse events." @default.
- W2007020183 created "2016-06-24" @default.
- W2007020183 creator A5015903274 @default.
- W2007020183 creator A5042758138 @default.
- W2007020183 creator A5073695437 @default.
- W2007020183 creator A5088304855 @default.
- W2007020183 date "2010-01-01" @default.
- W2007020183 modified "2023-09-25" @default.
- W2007020183 title "Colorectal Cancer: Focus on Capecitabine" @default.
- W2007020183 cites W1490790087 @default.
- W2007020183 cites W1905936368 @default.
- W2007020183 cites W1919810009 @default.
- W2007020183 cites W1929698530 @default.
- W2007020183 cites W1941365207 @default.
- W2007020183 cites W1963578655 @default.
- W2007020183 cites W1968376057 @default.
- W2007020183 cites W1968463676 @default.
- W2007020183 cites W1971827763 @default.
- W2007020183 cites W1972320730 @default.
- W2007020183 cites W1977524408 @default.
- W2007020183 cites W1980762644 @default.
- W2007020183 cites W1990814796 @default.
- W2007020183 cites W1992139037 @default.
- W2007020183 cites W1993386240 @default.
- W2007020183 cites W1993517991 @default.
- W2007020183 cites W2017648280 @default.
- W2007020183 cites W2017654486 @default.
- W2007020183 cites W2030395635 @default.
- W2007020183 cites W2032229951 @default.
- W2007020183 cites W2032375768 @default.
- W2007020183 cites W2044970916 @default.
- W2007020183 cites W2050083434 @default.
- W2007020183 cites W2052055688 @default.
- W2007020183 cites W2057348314 @default.
- W2007020183 cites W2058453858 @default.
- W2007020183 cites W2074075785 @default.
- W2007020183 cites W2074307321 @default.
- W2007020183 cites W2075925486 @default.
- W2007020183 cites W2083514719 @default.
- W2007020183 cites W2085079161 @default.
- W2007020183 cites W2085705101 @default.
- W2007020183 cites W2086873616 @default.
- W2007020183 cites W2096689681 @default.
- W2007020183 cites W2097158913 @default.
- W2007020183 cites W2113818241 @default.
- W2007020183 cites W2113919377 @default.
- W2007020183 cites W2114780052 @default.
- W2007020183 cites W2117777958 @default.
- W2007020183 cites W2119045502 @default.
- W2007020183 cites W2121313610 @default.
- W2007020183 cites W2121368761 @default.
- W2007020183 cites W2121708973 @default.
- W2007020183 cites W2122136304 @default.
- W2007020183 cites W2122900223 @default.
- W2007020183 cites W2123811123 @default.
- W2007020183 cites W2124410855 @default.
- W2007020183 cites W2125447919 @default.
- W2007020183 cites W2127500959 @default.
- W2007020183 cites W2127862903 @default.
- W2007020183 cites W2128447158 @default.
- W2007020183 cites W2129408765 @default.
- W2007020183 cites W2130647939 @default.
- W2007020183 cites W2132545630 @default.
- W2007020183 cites W2133671458 @default.
- W2007020183 cites W2137408681 @default.
- W2007020183 cites W2140626944 @default.
- W2007020183 cites W2143743735 @default.
- W2007020183 cites W2143769865 @default.
- W2007020183 cites W2143938997 @default.
- W2007020183 cites W2146161922 @default.
- W2007020183 cites W2148566563 @default.
- W2007020183 cites W2154662994 @default.
- W2007020183 cites W2156147330 @default.
- W2007020183 cites W2162017067 @default.
- W2007020183 cites W2162158906 @default.
- W2007020183 cites W2162315065 @default.
- W2007020183 cites W2165429160 @default.
- W2007020183 cites W2171232394 @default.
- W2007020183 cites W2205981120 @default.
- W2007020183 cites W2210225408 @default.
- W2007020183 cites W2227478494 @default.
- W2007020183 cites W2314927739 @default.
- W2007020183 cites W2973265150 @default.
- W2007020183 doi "https://doi.org/10.4137/cmro.s1599" @default.
- W2007020183 hasPublicationYear "2010" @default.
- W2007020183 type Work @default.
- W2007020183 sameAs 2007020183 @default.
- W2007020183 citedByCount "1" @default.
- W2007020183 countsByYear W20070201832018 @default.
- W2007020183 crossrefType "journal-article" @default.
- W2007020183 hasAuthorship W2007020183A5015903274 @default.
- W2007020183 hasAuthorship W2007020183A5042758138 @default.
- W2007020183 hasAuthorship W2007020183A5073695437 @default.
- W2007020183 hasAuthorship W2007020183A5088304855 @default.
- W2007020183 hasConcept C121608353 @default.
- W2007020183 hasConcept C126322002 @default.
- W2007020183 hasConcept C143998085 @default.
- W2007020183 hasConcept C197934379 @default.
- W2007020183 hasConcept C2776694085 @default.
- W2007020183 hasConcept C2777802072 @default.