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- W2007051752 abstract "The importance of glycosylation in cell surface expression of muscarinic receptors in cultured guinea pig pancreatic acini was investigated. Recovery of the muscarinic receptor population after carbachol-induced down regulation was blocked by cycloheximide but not by tunicamycin, although tunicamycin reduced [3H]mannose incorporation into acinar macromolecules by up to 90%. Tunicamycin treatment also failed to alter carbachol stimulation of amylase secretion from cultured acini. These results indicate that glycosylation of the glandular subtype of muscarinic receptor in the pancreatic acinar cell is not necessary for its insertion in the plasma membrane or for its functional activity." @default.
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- W2007051752 date "1990-11-12" @default.
- W2007051752 modified "2023-09-30" @default.
- W2007051752 title "Effects of cycloheximide and tunicamycin on cell surface expression of pancreatic muscarinic acetylcholine receptors" @default.
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- W2007051752 doi "https://doi.org/10.1016/0014-5793(90)81323-g" @default.
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