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- W2007066337 abstract "Vol 349 • March 8, 1997 701 risk, whereas factors preventing ovulation, such as pregnancy and use of oral contraceptives, are protective. The rate of increase for the incidence of ovarian cancer diminishes after menopause. We speculate that initiating mutations accumulate during the repeated cycles of cell divisions that epithelial ovarian cells undergo with ovulation, thereby forming the basis for malignant transformation upon loss of chromosome 17. Our data show that this event increases with age. On the assumption that epithelial tumours have a common cellular origin and that specific mutational events contribute to tumour histology and grade, our hypothesis explains the non-random distribution with age of ovarian tumours of different histology." @default.
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- W2007066337 date "1997-03-01" @default.
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- W2007066337 title "Reduced acute rejection after liver transplantation with Neoral-based triple immunosuppression" @default.
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- W2007066337 doi "https://doi.org/10.1016/s0140-6736(05)60138-9" @default.
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