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- W2007069042 abstract "Plants have become, over the last ten years, a suitable alternative to microbial and animal cell factories for the production of clinically-useful, therapeutic proteins. Besides the well known advantage of low-cost and large-scale production of safe and biologically active mammalian proteins, plants also are able to perform most post-translational maturations required for biological activity and suitable pharmacokinetics of recombinant therapeutic proteins. In this short review we focus on glycosylation and proteolytic processing of plant-made pharmaceuticals during their transport through the plant cell's secretory pathway. We also address the practical implications of these important processes on the effectiveness of plant molecular pharming systems." @default.
- W2007069042 created "2016-06-24" @default.
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- W2007069042 date "2005-03-01" @default.
- W2007069042 modified "2023-10-18" @default.
- W2007069042 title "Protein modifications in the plant secretory pathway: current status and practical implications in molecular pharming" @default.
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- W2007069042 doi "https://doi.org/10.1016/j.vaccine.2004.11.003" @default.
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