Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007079285> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2007079285 endingPage "157" @default.
- W2007079285 startingPage "149" @default.
- W2007079285 abstract "To determine whether hyoscine has a sparing effect on the volume of dobutamine required to maintain mean arterial pressure (MAP) at 70 mmHg in horses anaesthetized with halothane.Prospective, randomized, controlled clinical trial.Twenty adult horses weighing 507 +/- 97 kg (mean +/- SD), aged 10 +/- 5 years.Pre-anaesthetic medication in all horses was intramuscular (IM) acepromazine (40 mug kg(-1)) and intravenous (IV) detomidine (0.02 mg kg(-1)). Anaesthesia was induced with ketamine (2.2 mg kg(-1) IV) and diazepam (0.02 mg kg(-1) IV), and maintained with halothane in oxygen. Horses breathed spontaneously. Flunixin (1.1 mg kg(-1) IV) was given to provide analgesia. Heart rate, ECG, invasive arterial pressure, respiratory rate, percentage end-tidal carbon dioxide, percentage end-tidal halothane and partial pressure of oxygen and carbon dioxide in arterial blood and blood pH were monitored. Dobutamine was infused by an infusion pump to maintain MAP at 70 mmHg. Horses were randomly assigned to receive saline or hyoscine (0.1 mg kg(-1)) IV 30 minutes after induction. The heart rate, MAP and volume of dobutamine infused over 30-minute periods were measured and analysed statistically using a one-way anova.After administration of hyoscine, heart rate increased for 10 minutes (p < 0.01) and MAP for 5 minutes (p < 0.01). There was no difference in the volume of dobutamine infused over 30 minutes between horses given hyoscine or saline, although there was a wide individual variation in dobutamine requirements. No side effects of hyoscine were seen.The increase in heart rate and blood pressure that occurs after 0.1 mg kg(-1) hyoscine is given IV in anaesthetized horses, is of short duration and does not significantly alter the amount of dobutamine required to maintain arterial pressure over the next 30 minutes. Clinical relevance The short duration of action of 0.1 mg kg(-1) hyoscine IV may limit its usefulness for correction of hypotension in horses anaesthetized with halothane. Further work is necessary to investigate the effects of higher or repeated doses or constant rate infusions of hyoscine." @default.
- W2007079285 created "2016-06-24" @default.
- W2007079285 creator A5034760942 @default.
- W2007079285 creator A5047533142 @default.
- W2007079285 date "2006-05-01" @default.
- W2007079285 modified "2023-10-03" @default.
- W2007079285 title "The effect of hyoscine on dobutamine requirement in spontaneously breathing horses anaesthetized with halothane" @default.
- W2007079285 cites W1966220338 @default.
- W2007079285 cites W1989465025 @default.
- W2007079285 cites W2002356413 @default.
- W2007079285 cites W2021456388 @default.
- W2007079285 cites W2027208808 @default.
- W2007079285 cites W2031702137 @default.
- W2007079285 cites W2043768313 @default.
- W2007079285 cites W2060776091 @default.
- W2007079285 cites W2069400818 @default.
- W2007079285 cites W2078618662 @default.
- W2007079285 cites W2081705928 @default.
- W2007079285 cites W2084989589 @default.
- W2007079285 cites W2086141974 @default.
- W2007079285 cites W2143874717 @default.
- W2007079285 cites W2146009111 @default.
- W2007079285 cites W2155466139 @default.
- W2007079285 cites W2159660533 @default.
- W2007079285 cites W2396667495 @default.
- W2007079285 doi "https://doi.org/10.1111/j.1467-2995.2005.00250.x" @default.
- W2007079285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16634940" @default.
- W2007079285 hasPublicationYear "2006" @default.
- W2007079285 type Work @default.
- W2007079285 sameAs 2007079285 @default.
- W2007079285 citedByCount "13" @default.
- W2007079285 countsByYear W20070792852012 @default.
- W2007079285 countsByYear W20070792852013 @default.
- W2007079285 countsByYear W20070792852014 @default.
- W2007079285 countsByYear W20070792852015 @default.
- W2007079285 countsByYear W20070792852019 @default.
- W2007079285 countsByYear W20070792852020 @default.
- W2007079285 crossrefType "journal-article" @default.
- W2007079285 hasAuthorship W2007079285A5034760942 @default.
- W2007079285 hasAuthorship W2007079285A5047533142 @default.
- W2007079285 hasBestOaLocation W20070792852 @default.
- W2007079285 hasConcept C126322002 @default.
- W2007079285 hasConcept C139940330 @default.
- W2007079285 hasConcept C178853913 @default.
- W2007079285 hasConcept C2776452961 @default.
- W2007079285 hasConcept C2776812421 @default.
- W2007079285 hasConcept C2776932660 @default.
- W2007079285 hasConcept C2777257755 @default.
- W2007079285 hasConcept C2777397205 @default.
- W2007079285 hasConcept C2777953023 @default.
- W2007079285 hasConcept C2779591255 @default.
- W2007079285 hasConcept C2780447015 @default.
- W2007079285 hasConcept C2780795376 @default.
- W2007079285 hasConcept C2781185063 @default.
- W2007079285 hasConcept C42219234 @default.
- W2007079285 hasConcept C534529494 @default.
- W2007079285 hasConcept C71924100 @default.
- W2007079285 hasConcept C8213797 @default.
- W2007079285 hasConcept C84393581 @default.
- W2007079285 hasConceptScore W2007079285C126322002 @default.
- W2007079285 hasConceptScore W2007079285C139940330 @default.
- W2007079285 hasConceptScore W2007079285C178853913 @default.
- W2007079285 hasConceptScore W2007079285C2776452961 @default.
- W2007079285 hasConceptScore W2007079285C2776812421 @default.
- W2007079285 hasConceptScore W2007079285C2776932660 @default.
- W2007079285 hasConceptScore W2007079285C2777257755 @default.
- W2007079285 hasConceptScore W2007079285C2777397205 @default.
- W2007079285 hasConceptScore W2007079285C2777953023 @default.
- W2007079285 hasConceptScore W2007079285C2779591255 @default.
- W2007079285 hasConceptScore W2007079285C2780447015 @default.
- W2007079285 hasConceptScore W2007079285C2780795376 @default.
- W2007079285 hasConceptScore W2007079285C2781185063 @default.
- W2007079285 hasConceptScore W2007079285C42219234 @default.
- W2007079285 hasConceptScore W2007079285C534529494 @default.
- W2007079285 hasConceptScore W2007079285C71924100 @default.
- W2007079285 hasConceptScore W2007079285C8213797 @default.
- W2007079285 hasConceptScore W2007079285C84393581 @default.
- W2007079285 hasIssue "3" @default.
- W2007079285 hasLocation W20070792851 @default.
- W2007079285 hasLocation W20070792852 @default.
- W2007079285 hasLocation W20070792853 @default.
- W2007079285 hasOpenAccess W2007079285 @default.
- W2007079285 hasPrimaryLocation W20070792851 @default.
- W2007079285 hasRelatedWork W1974978699 @default.
- W2007079285 hasRelatedWork W1988797425 @default.
- W2007079285 hasRelatedWork W2007079285 @default.
- W2007079285 hasRelatedWork W2025559964 @default.
- W2007079285 hasRelatedWork W2073060491 @default.
- W2007079285 hasRelatedWork W2135791818 @default.
- W2007079285 hasRelatedWork W2153604745 @default.
- W2007079285 hasRelatedWork W2238953091 @default.
- W2007079285 hasRelatedWork W2412958953 @default.
- W2007079285 hasRelatedWork W4238580458 @default.
- W2007079285 hasVolume "33" @default.
- W2007079285 isParatext "false" @default.
- W2007079285 isRetracted "false" @default.
- W2007079285 magId "2007079285" @default.
- W2007079285 workType "article" @default.