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• W2007091639 abstract "Two non-polar fractions viz. hexane (Hex-LI) and chloroform fraction (CHCl3-LI) of Lawsonia inermis were studied for their antiproliferative potential in various cancer cell lines viz. HeLa, MCF-7, A549 and C6 glioma cells. Both the fractions showed more than 60 % of growth inhibition in all the tested cell lines at highest tested concentration. In clonogenic assay, different concentrations of Hex-LI and CHCl3-LI decreased the number and size of colonies as compared to control in HeLa cells. The apoptotic effects as nuclear condensation, fragmentation were visualized with Hoechst-33342 staining of HeLa cells using confocal microscope. Both fractions induced apoptotic cell death in human cervical carcinoma (HeLa) cells as evident from flow cytometric analysis carried out using Annexin V-FITC and propidium iodide dyes. CHCl3-LI treated cells significantly induced apoptosis (25.43 %) in comparison to control. Results from Neutral Comet assay demonstrated that both fractions induced double stranded breaks (DSB's) in HeLa cells. Our data indicated that Hex-LI and CHCl3-LI treated cells showed significant increase of 32.2 and 18.56 % reactive oxygen species (ROS) levels in DCFH-DA assay respectively. Further, experimental studies to decipher exact pathway via which these fractions induce cell death are in progress." @default.
• W2007091639 created "2016-06-24" @default.
• W2007091639 creator A5037152480 @default.
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• W2007091639 creator A5055055138 @default.
• W2007091639 creator A5089435279 @default.
• W2007091639 date "2015-03-19" @default.
• W2007091639 modified "2023-10-01" @default.
• W2007091639 title "Antiproliferative and Apoptosis Inducing Effects of Non-Polar Fractions from Lawsonia inermis L. in Cervical (HeLa) Cancer Cells" @default.
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• W2007091639 cites W1892085233 @default.
• W2007091639 cites W1951658941 @default.
• W2007091639 cites W1965565026 @default.
• W2007091639 cites W1965606785 @default.
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• W2007091639 cites W1966827520 @default.
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• W2007091639 cites W1980463323 @default.
• W2007091639 cites W1981485783 @default.
• W2007091639 cites W1984329481 @default.
• W2007091639 cites W1987347109 @default.
• W2007091639 cites W1992335590 @default.
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• W2007091639 cites W2007150761 @default.
• W2007091639 cites W2008757142 @default.
• W2007091639 cites W2009491438 @default.
• W2007091639 cites W2011006339 @default.
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• W2007091639 cites W2019515718 @default.
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• W2007091639 cites W2036461645 @default.
• W2007091639 cites W2037323330 @default.
• W2007091639 cites W2043876718 @default.
• W2007091639 cites W2046145131 @default.
• W2007091639 cites W2046277450 @default.
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• W2007091639 doi "https://doi.org/10.1007/s12298-015-0285-3" @default.
• W2007091639 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4411381" @default.
• W2007091639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25931778" @default.
• W2007091639 hasPublicationYear "2015" @default.
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