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- W2007093892 abstract "This study examines sequence divergence in three spacer regions of the ribosomal DNA (rDNA) cistron, to test the hypothesis of unequal mutation rates. Portions of two transcribed spacers (ITS-1 and 5' ETS) and the non-transcribed spacer (NTS) or intergenic spacer (IGS) formed the basis of comparative analyses. Sequence divergence was measured both within an individual lake trout (Salvelinus namaycush) and among several related salmonid species (lake trout; brook trout, Salvelinus fontinalis; Arctic char, Salvelinus alpinus; Atlantic salmon, Salmo salar; and brown trout, Salmo trutta). Despite major differences in the length of the rDNA cistron within individual lake trout, minimal sequence difference was detected among cistrons. Interspecies comparisons found that molecular variation in the rDNA spacers did not conform to the predicted pattern of evolution (ITS spacers<ETS spacers<IGS). Specifically, the IGS contains a region that appears to be as highly, or more conserved than the ITS-1." @default.
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- W2007093892 date "2000-05-01" @default.
- W2007093892 modified "2023-09-27" @default.
- W2007093892 title "Comparative analysis of intra-individual and inter-species DNA sequence variation in salmonid ribosomal DNA cistrons" @default.
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- W2007093892 doi "https://doi.org/10.1016/s0378-1119(00)00156-6" @default.
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