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- W2007098787 endingPage "25" @default.
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- W2007098787 abstract "Cancer cells are resistant to conventional chemotherapy and radiotherapy, however, the molecular mechanisms of resistance to therapy remain unclear. Cellular survival machinery protects mitochondrial integrity against endogenous or exogenous stresses. Prodeath molecules orchestrate around mitochondria to initiate and execute cell death in cancer, and also play an underappreciated role in survival of cancer cells. Prosurvival mechanisms can operate at mitochondrial and postmitochondrial levels to attenuate core apoptotic death program. It is intriguing to explore how prosurvival and prodeath molecules crosstalk to regulate mitochondrial functions leading to increased cancer cell survival. This review describes some putative survival mechanisms at mitochondria, which may play a role in designing effective agents for cancer prevention and therapy. These survival pathways may also have significance in understanding other human pathophysiological conditions including diabetes, cardiovascular, autoimmune, and neurodegenerative diseases." @default.
- W2007098787 created "2016-06-24" @default.
- W2007098787 creator A5012219857 @default.
- W2007098787 creator A5012502014 @default.
- W2007098787 date "2014-05-01" @default.
- W2007098787 modified "2023-09-28" @default.
- W2007098787 title "Mitochondrial and postmitochondrial survival signaling in cancer" @default.
- W2007098787 cites W1506642042 @default.
- W2007098787 cites W1515506492 @default.
- W2007098787 cites W1557686543 @default.
- W2007098787 cites W1575666495 @default.
- W2007098787 cites W1607777232 @default.
- W2007098787 cites W1616121322 @default.
- W2007098787 cites W1617532721 @default.
- W2007098787 cites W1634577033 @default.
- W2007098787 cites W1644794975 @default.
- W2007098787 cites W1678800844 @default.
- W2007098787 cites W1793304642 @default.
- W2007098787 cites W1952459948 @default.
- W2007098787 cites W1964625584 @default.
- W2007098787 cites W1964976203 @default.
- W2007098787 cites W1966176339 @default.
- W2007098787 cites W1967203467 @default.
- W2007098787 cites W1968854074 @default.
- W2007098787 cites W1969093459 @default.
- W2007098787 cites W1969855050 @default.
- W2007098787 cites W1970101464 @default.
- W2007098787 cites W1971206408 @default.
- W2007098787 cites W1971794516 @default.
- W2007098787 cites W1973206036 @default.
- W2007098787 cites W1975731421 @default.
- W2007098787 cites W1976065095 @default.
- W2007098787 cites W1976141746 @default.
- W2007098787 cites W1977838124 @default.
- W2007098787 cites W1979039759 @default.
- W2007098787 cites W1979385451 @default.
- W2007098787 cites W1979842763 @default.
- W2007098787 cites W1980706265 @default.
- W2007098787 cites W1980762570 @default.
- W2007098787 cites W1983167566 @default.
- W2007098787 cites W1984046437 @default.
- W2007098787 cites W1986396787 @default.
- W2007098787 cites W1986568749 @default.
- W2007098787 cites W1986717393 @default.
- W2007098787 cites W1986889175 @default.
- W2007098787 cites W1988917342 @default.
- W2007098787 cites W1990623889 @default.
- W2007098787 cites W1992089548 @default.
- W2007098787 cites W1992196716 @default.
- W2007098787 cites W1992989336 @default.
- W2007098787 cites W1993481241 @default.
- W2007098787 cites W1994527193 @default.
- W2007098787 cites W1994971983 @default.
- W2007098787 cites W1996349676 @default.
- W2007098787 cites W1996743951 @default.
- W2007098787 cites W1997879915 @default.
- W2007098787 cites W1998206810 @default.
- W2007098787 cites W1999057673 @default.
- W2007098787 cites W1999710434 @default.
- W2007098787 cites W2000623989 @default.
- W2007098787 cites W2000907682 @default.
- W2007098787 cites W2000989775 @default.
- W2007098787 cites W2001258946 @default.
- W2007098787 cites W2001372725 @default.
- W2007098787 cites W2001543531 @default.
- W2007098787 cites W2001830362 @default.
- W2007098787 cites W2002145400 @default.
- W2007098787 cites W2002544384 @default.
- W2007098787 cites W2003152111 @default.
- W2007098787 cites W2005282780 @default.
- W2007098787 cites W2007917384 @default.
- W2007098787 cites W2009102003 @default.
- W2007098787 cites W2009194850 @default.
- W2007098787 cites W2009221661 @default.
- W2007098787 cites W2009866554 @default.
- W2007098787 cites W2009967533 @default.
- W2007098787 cites W2011082535 @default.
- W2007098787 cites W2011125717 @default.
- W2007098787 cites W2011344898 @default.
- W2007098787 cites W2012173926 @default.
- W2007098787 cites W2015317524 @default.
- W2007098787 cites W2017275974 @default.
- W2007098787 cites W2018439544 @default.
- W2007098787 cites W2019562799 @default.
- W2007098787 cites W2020448280 @default.
- W2007098787 cites W2021581111 @default.
- W2007098787 cites W2022131685 @default.
- W2007098787 cites W2022569128 @default.
- W2007098787 cites W2023051812 @default.
- W2007098787 cites W2023973783 @default.
- W2007098787 cites W2024306318 @default.
- W2007098787 cites W2025128734 @default.
- W2007098787 cites W2026228428 @default.
- W2007098787 cites W2026514003 @default.
- W2007098787 cites W2026926408 @default.
- W2007098787 cites W2028083589 @default.
- W2007098787 cites W2029801534 @default.
- W2007098787 cites W2033089897 @default.