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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007100984> ?p ?o ?g. }

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• W2007100984 abstract "SAR studies were conducted around lead compound 1 using high-throughput parallel solution and solid phase synthesis. Our lead optimization efforts led to the identification of several CCR2b antagonists with potent activity in both binding and functional assays [Compound 71 CCR2b Binding IC50 3.2 nM; MCP-1-Induced Chemotaxis IC50 0.83 nM; Ca2+ Flux IC50 7.5 nM]." @default.
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• W2007100984 date "2008-03-01" @default.
• W2007100984 modified "2023-10-17" @default.
• W2007100984 title "Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series" @default.
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• W2007100984 doi "https://doi.org/10.1016/j.bmcl.2008.02.015" @default.
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