Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007124329> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2007124329 endingPage "770" @default.
- W2007124329 startingPage "763" @default.
- W2007124329 abstract "In an extract of Ehrlich ascites tumor (EAT) cells which had been “preincubated” for 45 min to lower endogenous protein synthesis (S30C) the translation of exogenous encephalomyocarditis (EMC) viral mRNA proceeds at a constant rate for over 90 min. In a similarly treated extract of interferon-treated EAT cells (S30INT) the translation proceeds at a lower rate than in the S30C for about 30 min and then stops. The impairment of the translation in the S30INT is mediated by one or more inhibitors. After the cessation of translation the viral mRNA in the S30INT is in large polysomes. The size of these changes little (if any) during a further 15 min incubation. The addition of mouse tRNA (but not ribosomal RNA or E. coli tRNA) to the S30INT after the cessation of viral mRNA translation results in the restart of translation at a rate close to that in the S30C. This effect of tRNA is diminished by pactamycin, which inhibits peptide chain initiation but not elongation. These results indicate that addition of tRNA allows the elongation of incomplete peptide chains and the initiation of new chains. The need for added tRNA may be due to the fact that in S30INT the amino acid acceptance of some of the endogenous tRNA species (but not of added tRNAs) is impaired. This impairment is pronounced for leucine and very slight, if any, for five other amino acids tested (i.e. isoleucine, methionine, phenylalanine, threonine, and valine)." @default.
- W2007124329 created "2016-06-24" @default.
- W2007124329 creator A5028453293 @default.
- W2007124329 creator A5034783926 @default.
- W2007124329 creator A5056435911 @default.
- W2007124329 date "1974-04-01" @default.
- W2007124329 modified "2023-09-26" @default.
- W2007124329 title "Release of the inhibition of messenger RNA translation in extracts of interferon-treated ehrlich ascites tumor cells by added transfer RNA" @default.
- W2007124329 cites W1507509336 @default.
- W2007124329 cites W1980645367 @default.
- W2007124329 cites W2005939414 @default.
- W2007124329 cites W2007554410 @default.
- W2007124329 cites W2032807009 @default.
- W2007124329 cites W2035918947 @default.
- W2007124329 cites W2068400576 @default.
- W2007124329 cites W2164102919 @default.
- W2007124329 doi "https://doi.org/10.1016/0006-291x(74)90612-3" @default.
- W2007124329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4363942" @default.
- W2007124329 hasPublicationYear "1974" @default.
- W2007124329 type Work @default.
- W2007124329 sameAs 2007124329 @default.
- W2007124329 citedByCount "68" @default.
- W2007124329 crossrefType "journal-article" @default.
- W2007124329 hasAuthorship W2007124329A5028453293 @default.
- W2007124329 hasAuthorship W2007124329A5034783926 @default.
- W2007124329 hasAuthorship W2007124329A5056435911 @default.
- W2007124329 hasConcept C104317684 @default.
- W2007124329 hasConcept C105580179 @default.
- W2007124329 hasConcept C149364088 @default.
- W2007124329 hasConcept C153911025 @default.
- W2007124329 hasConcept C153957851 @default.
- W2007124329 hasConcept C159047783 @default.
- W2007124329 hasConcept C185592680 @default.
- W2007124329 hasConcept C2776178377 @default.
- W2007124329 hasConcept C2776580952 @default.
- W2007124329 hasConcept C2777305461 @default.
- W2007124329 hasConcept C2777431362 @default.
- W2007124329 hasConcept C2777573094 @default.
- W2007124329 hasConcept C2778403015 @default.
- W2007124329 hasConcept C2780912031 @default.
- W2007124329 hasConcept C3675279 @default.
- W2007124329 hasConcept C515207424 @default.
- W2007124329 hasConcept C55493867 @default.
- W2007124329 hasConcept C65666806 @default.
- W2007124329 hasConcept C67705224 @default.
- W2007124329 hasConcept C86803240 @default.
- W2007124329 hasConcept C88478588 @default.
- W2007124329 hasConceptScore W2007124329C104317684 @default.
- W2007124329 hasConceptScore W2007124329C105580179 @default.
- W2007124329 hasConceptScore W2007124329C149364088 @default.
- W2007124329 hasConceptScore W2007124329C153911025 @default.
- W2007124329 hasConceptScore W2007124329C153957851 @default.
- W2007124329 hasConceptScore W2007124329C159047783 @default.
- W2007124329 hasConceptScore W2007124329C185592680 @default.
- W2007124329 hasConceptScore W2007124329C2776178377 @default.
- W2007124329 hasConceptScore W2007124329C2776580952 @default.
- W2007124329 hasConceptScore W2007124329C2777305461 @default.
- W2007124329 hasConceptScore W2007124329C2777431362 @default.
- W2007124329 hasConceptScore W2007124329C2777573094 @default.
- W2007124329 hasConceptScore W2007124329C2778403015 @default.
- W2007124329 hasConceptScore W2007124329C2780912031 @default.
- W2007124329 hasConceptScore W2007124329C3675279 @default.
- W2007124329 hasConceptScore W2007124329C515207424 @default.
- W2007124329 hasConceptScore W2007124329C55493867 @default.
- W2007124329 hasConceptScore W2007124329C65666806 @default.
- W2007124329 hasConceptScore W2007124329C67705224 @default.
- W2007124329 hasConceptScore W2007124329C86803240 @default.
- W2007124329 hasConceptScore W2007124329C88478588 @default.
- W2007124329 hasIssue "3" @default.
- W2007124329 hasLocation W20071243291 @default.
- W2007124329 hasLocation W20071243292 @default.
- W2007124329 hasOpenAccess W2007124329 @default.
- W2007124329 hasPrimaryLocation W20071243291 @default.
- W2007124329 hasRelatedWork W1537502381 @default.
- W2007124329 hasRelatedWork W1917485103 @default.
- W2007124329 hasRelatedWork W1990716676 @default.
- W2007124329 hasRelatedWork W2006485103 @default.
- W2007124329 hasRelatedWork W2060798604 @default.
- W2007124329 hasRelatedWork W2115858258 @default.
- W2007124329 hasRelatedWork W2183856975 @default.
- W2007124329 hasRelatedWork W2217118582 @default.
- W2007124329 hasRelatedWork W2417319957 @default.
- W2007124329 hasRelatedWork W2473103804 @default.
- W2007124329 hasVolume "57" @default.
- W2007124329 isParatext "false" @default.
- W2007124329 isRetracted "false" @default.
- W2007124329 magId "2007124329" @default.
- W2007124329 workType "article" @default.