FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007131837> ?p ?o ?g. }

• W2007131837 endingPage "2058" @default.
• W2007131837 startingPage "2046" @default.
• W2007131837 abstract "The complex formed by U1A RBD1 and the U1 snRNA stem/loop II is noted for its high affinity and exquisite specificity. Here, that complex is investigated by 5 ns molecular dynamics simulations and analyzed by reorientational eigenmode dynamics to determine the dynamic properties of the RNA:protein interface that could contribute to the binding mechanism. The analysis shows that there is extensive correlation between motions of the RNA and protein, involving 7 of the 10 RNA loop nucleotides, the protein β-sheet surface, two of its loops, and its C-terminal tripeptide sequence. Order parameters of these regions of the complex are uniformly high, indicating restricted motion. However, several regions of both RNA and protein retain local flexibility, notably three nucleotides of the RNA loop and one loop of RBD1 that does not contact RNA. The highly correlated motions involving both molecules reflect the intricate network of interactions that characterize this complex and could account in part for the thermodynamic coupling observed for complex formation." @default.
• W2007131837 created "2016-06-24" @default.
• W2007131837 creator A5047930774 @default.
• W2007131837 creator A5077603599 @default.
• W2007131837 date "2005-09-01" @default.
• W2007131837 modified "2023-10-11" @default.
• W2007131837 title "Correlated Motions in the U1 snRNA Stem/Loop 2:U1A RBD1 Complex" @default.
• W2007131837 cites W1572030366 @default.
• W2007131837 cites W1688901160 @default.
• W2007131837 cites W1967554461 @default.
• W2007131837 cites W1975038024 @default.
• W2007131837 cites W1976499671 @default.
• W2007131837 cites W1980096142 @default.
• W2007131837 cites W1981208472 @default.
• W2007131837 cites W1993926172 @default.
• W2007131837 cites W2010736683 @default.
• W2007131837 cites W2019160077 @default.
• W2007131837 cites W2023563495 @default.
• W2007131837 cites W2025717854 @default.
• W2007131837 cites W2034890717 @default.
• W2007131837 cites W2037461640 @default.
• W2007131837 cites W2043416802 @default.
• W2007131837 cites W2053590485 @default.
• W2007131837 cites W2056263922 @default.
• W2007131837 cites W2076599706 @default.
• W2007131837 cites W2076876382 @default.
• W2007131837 cites W2077689499 @default.
• W2007131837 cites W2089451977 @default.
• W2007131837 cites W2105835385 @default.
• W2007131837 cites W2106140689 @default.
• W2007131837 cites W2106527646 @default.
• W2007131837 cites W2114876189 @default.
• W2007131837 cites W2122199548 @default.
• W2007131837 cites W2138295147 @default.
• W2007131837 cites W2139339205 @default.
• W2007131837 cites W2153762874 @default.
• W2007131837 cites W2164460047 @default.
• W2007131837 cites W2276090646 @default.
• W2007131837 cites W2382256139 @default.
• W2007131837 cites W259468590 @default.
• W2007131837 cites W77934935 @default.
• W2007131837 cites W988018279 @default.
• W2007131837 doi "https://doi.org/10.1529/biophysj.104.058032" @default.
• W2007131837 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1366707" @default.
• W2007131837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15951381" @default.
• W2007131837 hasPublicationYear "2005" @default.
• W2007131837 type Work @default.
• W2007131837 sameAs 2007131837 @default.
• W2007131837 citedByCount "30" @default.
• W2007131837 countsByYear W20071318372012 @default.
• W2007131837 countsByYear W20071318372013 @default.
• W2007131837 countsByYear W20071318372014 @default.
• W2007131837 countsByYear W20071318372017 @default.
• W2007131837 countsByYear W20071318372019 @default.
• W2007131837 countsByYear W20071318372020 @default.
• W2007131837 countsByYear W20071318372021 @default.
• W2007131837 crossrefType "journal-article" @default.
• W2007131837 hasAuthorship W2007131837A5047930774 @default.
• W2007131837 hasAuthorship W2007131837A5077603599 @default.
• W2007131837 hasBestOaLocation W20071318371 @default.
• W2007131837 hasConcept C100299639 @default.
• W2007131837 hasConcept C104317684 @default.
• W2007131837 hasConcept C114614502 @default.
• W2007131837 hasConcept C12554922 @default.
• W2007131837 hasConcept C147597530 @default.
• W2007131837 hasConcept C167392928 @default.
• W2007131837 hasConcept C169663058 @default.
• W2007131837 hasConcept C184670325 @default.
• W2007131837 hasConcept C185592680 @default.
• W2007131837 hasConcept C194993378 @default.
• W2007131837 hasConcept C33923547 @default.
• W2007131837 hasConcept C512185932 @default.
• W2007131837 hasConcept C515207424 @default.
• W2007131837 hasConcept C55493867 @default.
• W2007131837 hasConcept C59593255 @default.
• W2007131837 hasConcept C67705224 @default.
• W2007131837 hasConcept C68483431 @default.
• W2007131837 hasConcept C75934600 @default.
• W2007131837 hasConcept C86803240 @default.
• W2007131837 hasConceptScore W2007131837C100299639 @default.
• W2007131837 hasConceptScore W2007131837C104317684 @default.
• W2007131837 hasConceptScore W2007131837C114614502 @default.
• W2007131837 hasConceptScore W2007131837C12554922 @default.
• W2007131837 hasConceptScore W2007131837C147597530 @default.
• W2007131837 hasConceptScore W2007131837C167392928 @default.
• W2007131837 hasConceptScore W2007131837C169663058 @default.
• W2007131837 hasConceptScore W2007131837C184670325 @default.
• W2007131837 hasConceptScore W2007131837C185592680 @default.
• W2007131837 hasConceptScore W2007131837C194993378 @default.
• W2007131837 hasConceptScore W2007131837C33923547 @default.
• W2007131837 hasConceptScore W2007131837C512185932 @default.
• W2007131837 hasConceptScore W2007131837C515207424 @default.
• W2007131837 hasConceptScore W2007131837C55493867 @default.
• W2007131837 hasConceptScore W2007131837C59593255 @default.
• W2007131837 hasConceptScore W2007131837C67705224 @default.
• W2007131837 hasConceptScore W2007131837C68483431 @default.
• W2007131837 hasConceptScore W2007131837C75934600 @default.
• W2007131837 hasConceptScore W2007131837C86803240 @default.

• next