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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007134093> ?p ?o ?g. }

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• W2007134093 abstract "We describe a cardiac muscle isoform of the voltage-dependent calcium channel alpha1 subunit, which corresponds to the rabbit ortholog of alpha1C-a (Cav1.2a). We also cloned smooth muscle isoforms alpha1C-b (Cav1.2b) and alpha1C-d (Cav1.2d). Differences among these three isoforms lie within the N-terminal region (exon 1A or 1B), the sixth transmembrane segment of domain I (exon 8A or 8B), and the use of exon 10, which forms the intracellular loop between transmembrane domains I and II. Two-hybrid analysis revealed interactions among the three alpha1 isoforms and beta subunits. In vitro overlay and immunoprecipitation analyses revealed preferential binding between alpha1C-a and beta2, which is also expressed at a high level in the heart." @default.
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• W2007134093 date "2006-07-01" @default.
• W2007134093 modified "2023-09-27" @default.
• W2007134093 title "Identification of a cardiac isoform of the murine calcium channel α1C (Cav1.2-a) subunit and its preferential binding with the β2 subunit" @default.
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• W2007134093 doi "https://doi.org/10.1016/j.yjmcc.2006.05.002" @default.
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