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- W2007136171 abstract "This study examined the effects of propranolol vs. placebo, administered immediately after a “retrieval” session of cocaine cue exposure (CCE), on craving and physiological responses occurring 24 h later during a subsequent “test” session of CCE. It was hypothesized that compared to placebo-treated cocaine-dependent (CD) individuals, propranolol-treated CD individuals would evidence attenuated craving and physiological reactivity during the test session. Secondarily, it was expected that group differences identified in the test session would be evident at a 1-week follow-up CCE session. Exploratory analyses of treatment effects on cocaine use were also performed at follow-up. CD participants received either 40 mg propranolol or placebo immediately following a “retrieval” CCE session. The next day, participants received a “test” session of CCE that was identical to the “retrieval” session except no medication was administered. Participants underwent a “follow-up” CCE session 1 week later. Craving and other reactivity measures were obtained at multiple time points during the CCE sessions. Propranolol- vs. placebo-treated participants evidenced significantly greater attenuation of craving and cardiovascular reactivity during the test session. Analysis of the follow-up CCE session data did not reveal any group differences. Although there was no evidence of treatment effects on cocaine use during follow-up, this study was insufficiently powered to rigorously evaluate differential cocaine use. This double-blind, placebo-controlled laboratory study provides the first evidence that propranolol administration following CCE may modulate memories for learning processes that subserve cocaine craving/cue reactivity in CD humans. Alternative interpretations of the findings were considered, and implications of the results for treatment were noted." @default.
- W2007136171 created "2016-06-24" @default.
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- W2007136171 date "2013-03-05" @default.
- W2007136171 modified "2023-10-07" @default.
- W2007136171 title "A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans" @default.
- W2007136171 cites W1475474724 @default.
- W2007136171 cites W1861723710 @default.
- W2007136171 cites W1892150242 @default.
- W2007136171 cites W1964186645 @default.
- W2007136171 cites W1964908467 @default.
- W2007136171 cites W1968735060 @default.
- W2007136171 cites W1968945175 @default.
- W2007136171 cites W1970316545 @default.
- W2007136171 cites W1970885260 @default.
- W2007136171 cites W1972985959 @default.
- W2007136171 cites W1977790476 @default.
- W2007136171 cites W1982137323 @default.
- W2007136171 cites W1982283217 @default.
- W2007136171 cites W1982333295 @default.
- W2007136171 cites W1982996925 @default.
- W2007136171 cites W1988132969 @default.
- W2007136171 cites W1997116342 @default.
- W2007136171 cites W1998607602 @default.
- W2007136171 cites W2002072526 @default.
- W2007136171 cites W2002503135 @default.
- W2007136171 cites W2002928138 @default.
- W2007136171 cites W2005641815 @default.
- W2007136171 cites W2012804248 @default.
- W2007136171 cites W2017375649 @default.
- W2007136171 cites W2018187135 @default.
- W2007136171 cites W2018929584 @default.
- W2007136171 cites W2019401805 @default.
- W2007136171 cites W2020280842 @default.
- W2007136171 cites W2020365906 @default.
- W2007136171 cites W2020443900 @default.
- W2007136171 cites W2022022688 @default.
- W2007136171 cites W2022818180 @default.
- W2007136171 cites W2024117415 @default.
- W2007136171 cites W2025672359 @default.
- W2007136171 cites W2027731726 @default.
- W2007136171 cites W2036077696 @default.
- W2007136171 cites W2038680295 @default.
- W2007136171 cites W2043662856 @default.
- W2007136171 cites W2043713058 @default.
- W2007136171 cites W2058421539 @default.
- W2007136171 cites W2061996597 @default.
- W2007136171 cites W2065631743 @default.
- W2007136171 cites W2067602621 @default.
- W2007136171 cites W2067812968 @default.
- W2007136171 cites W2068143995 @default.
- W2007136171 cites W2076626576 @default.
- W2007136171 cites W2077348308 @default.
- W2007136171 cites W2077496557 @default.
- W2007136171 cites W2078681519 @default.
- W2007136171 cites W2083217020 @default.
- W2007136171 cites W2089488334 @default.
- W2007136171 cites W2094206425 @default.
- W2007136171 cites W2103274844 @default.
- W2007136171 cites W2104643304 @default.
- W2007136171 cites W2108393262 @default.
- W2007136171 cites W2112358513 @default.
- W2007136171 cites W2115818949 @default.
- W2007136171 cites W2115906580 @default.
- W2007136171 cites W2126502833 @default.
- W2007136171 cites W2130108344 @default.
- W2007136171 cites W2139171499 @default.
- W2007136171 cites W2139788233 @default.
- W2007136171 cites W2145186621 @default.
- W2007136171 cites W2147424047 @default.
- W2007136171 cites W2148006968 @default.
- W2007136171 cites W2151704764 @default.
- W2007136171 cites W2152706970 @default.
- W2007136171 cites W2156010125 @default.
- W2007136171 cites W2161113761 @default.
- W2007136171 cites W2162887031 @default.
- W2007136171 cites W2162968165 @default.
- W2007136171 cites W2164751282 @default.
- W2007136171 cites W2167696282 @default.
- W2007136171 cites W2168783863 @default.
- W2007136171 cites W2324479456 @default.
- W2007136171 cites W2338674207 @default.
- W2007136171 cites W2405992154 @default.
- W2007136171 cites W2615800479 @default.
- W2007136171 cites W4229632460 @default.
- W2007136171 cites W4233385344 @default.
- W2007136171 cites W4233818199 @default.
- W2007136171 cites W4377217328 @default.
- W2007136171 cites W49548850 @default.
- W2007136171 cites W2065326872 @default.
- W2007136171 doi "https://doi.org/10.1007/s00213-013-3039-3" @default.