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• W2007140681 abstract "Primary immune deficiencies comprise a variety of genetic defects that affect development and/or function of the immune system. Among them, severe combined immune deficiencies (SCID) represent the most severe forms, and are, because of defects of T-lymphocyte development, sometimes associated with defects of other lymphoid lineages. Careful analysis of patients with SCID has been essential to define the genetic and immunological bases of these disorders. Understanding the pathophysiology of SCID has led to novel forms of treatment, based on stem cell transplantation and gene therapy." @default.
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• W2007140681 date "2004-12-01" @default.
• W2007140681 modified "2023-09-25" @default.
• W2007140681 title "Mechanisms of primary immunodeficiencies: from bed-side to bench and back" @default.
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• W2007140681 doi "https://doi.org/10.1016/j.ddmec.2004.10.008" @default.
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