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- W2007145655 abstract "Mixtures of aztreonam, 2S-[2α, 3β(Z)]-2-[[[1-(2-amino-4-thiazolyl-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl) amino]-2-oxo-ethylidine]amino]oxy]-2-methyl-propanoic acid, and L-arginine are assayed by peak-to-baseline, peak-to-peak, and zero-crossing second-derivative spectrophotometry. Aztreonam is the first of a new class of beta-lactam antibiotics (i.e., the mono-bactam antibiotics, highly effective against aerobic gram-negative bacteria). Beer's law is followed for up to 31 μg/mL of aztreonam and L-arginine in the presence of one another. Detection limits at the p = 0.05 level of significance range from 0.11 to 0.37 μg/mL. The method was successfully applied to laboratory mixtures and commercial injections containing these substances." @default.
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- W2007145655 date "1990-03-01" @default.
- W2007145655 modified "2023-09-27" @default.
- W2007145655 title "Simultaneous Derivative Spectrophotometric Determination of Aztreonam and L-Arginine in Injections" @default.
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- W2007145655 doi "https://doi.org/10.1002/jps.2600790317" @default.
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