FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007145808> ?p ?o ?g. }

• W2007145808 endingPage "e25980" @default.
• W2007145808 startingPage "e25980" @default.
• W2007145808 abstract "Diatoms are ubiquitous and abundant primary producers that have been traditionally considered as a beneficial food source for grazers and for the transfer of carbon through marine food webs. However, many diatom species produce polyunsaturated aldehydes that disrupt development in the offspring of grazers that feed on these unicellular algae. Here we provide evidence that production of the physiological messenger nitric oxide increases after treatment with the polyunsaturated aldehyde decadienal in embryos of the sea urchin Paracentrotus lividus. At high decadienal concentrations, nitric oxide mediates initial apoptotic events leading to loss of mitochondrial functionality through the generation of peroxynitrite. At low decadienal concentrations, nitric oxide contributes to the activation of hsp70 gene expression thereby protecting embryos against the toxic effects of this aldehyde. When nitric oxide levels were lowered by inhibiting nitric oxide synthase activity, the expression of hsp70 in swimming blastula decreased and the proportion of abnormal plutei increased. However, in later pluteus stages nitric oxide was no longer able to exert this protective function: hsp70 and nitric oxide synthase expression decreased with a consequent increase in the expression of caspase-8. Our findings that nitric oxide production increases rapidly in response to a toxic exogenous stimulus opens new perspectives on the possible role of this gas as an important messenger to environmental stress in sea urchins and for understanding the cellular mechanisms underlying toxicity during diatom blooms." @default.
• W2007145808 created "2016-06-24" @default.
• W2007145808 creator A5001527570 @default.
• W2007145808 creator A5059309264 @default.
• W2007145808 creator A5061942052 @default.
• W2007145808 creator A5070369844 @default.
• W2007145808 creator A5089697692 @default.
• W2007145808 date "2011-10-11" @default.
• W2007145808 modified "2023-10-12" @default.
• W2007145808 title "Nitric Oxide Mediates the Stress Response Induced by Diatom Aldehydes in the Sea Urchin Paracentrotus lividus" @default.
• W2007145808 cites W1499500424 @default.
• W2007145808 cites W1555181274 @default.
• W2007145808 cites W1963887696 @default.
• W2007145808 cites W1970436607 @default.
• W2007145808 cites W1970438344 @default.
• W2007145808 cites W1973731340 @default.
• W2007145808 cites W1981287076 @default.
• W2007145808 cites W1985550504 @default.
• W2007145808 cites W1987502441 @default.
• W2007145808 cites W1987532345 @default.
• W2007145808 cites W1987603536 @default.
• W2007145808 cites W1991692667 @default.
• W2007145808 cites W1993613556 @default.
• W2007145808 cites W1995993324 @default.
• W2007145808 cites W1996800520 @default.
• W2007145808 cites W1998261600 @default.
• W2007145808 cites W2000665055 @default.
• W2007145808 cites W2001566039 @default.
• W2007145808 cites W2003496952 @default.
• W2007145808 cites W2007621070 @default.
• W2007145808 cites W2008813612 @default.
• W2007145808 cites W2010380872 @default.
• W2007145808 cites W2012101041 @default.
• W2007145808 cites W2015097842 @default.
• W2007145808 cites W2026013371 @default.
• W2007145808 cites W2029753980 @default.
• W2007145808 cites W2033900018 @default.
• W2007145808 cites W2044005418 @default.
• W2007145808 cites W2049460970 @default.
• W2007145808 cites W2051471245 @default.
• W2007145808 cites W2055465485 @default.
• W2007145808 cites W2055708496 @default.
• W2007145808 cites W2061426692 @default.
• W2007145808 cites W2070558188 @default.
• W2007145808 cites W2073911245 @default.
• W2007145808 cites W2080742860 @default.
• W2007145808 cites W2084454352 @default.
• W2007145808 cites W2084517753 @default.
• W2007145808 cites W2085677815 @default.
• W2007145808 cites W2087887426 @default.
• W2007145808 cites W2087979833 @default.
• W2007145808 cites W2094414155 @default.
• W2007145808 cites W2094690394 @default.
• W2007145808 cites W2097551961 @default.
• W2007145808 cites W2099249565 @default.
• W2007145808 cites W2108244474 @default.
• W2007145808 cites W2112100482 @default.
• W2007145808 cites W2114868510 @default.
• W2007145808 cites W2121718052 @default.
• W2007145808 cites W2123114095 @default.
• W2007145808 cites W2123345322 @default.
• W2007145808 cites W2131537381 @default.
• W2007145808 cites W2133994616 @default.
• W2007145808 cites W2140476488 @default.
• W2007145808 cites W2140652267 @default.
• W2007145808 cites W2146032953 @default.
• W2007145808 cites W2148316715 @default.
• W2007145808 cites W2148573587 @default.
• W2007145808 cites W2153085302 @default.
• W2007145808 cites W2157523980 @default.
• W2007145808 cites W2158667917 @default.
• W2007145808 cites W2159978417 @default.
• W2007145808 cites W2396285955 @default.
• W2007145808 cites W2415160044 @default.
• W2007145808 cites W2957351734 @default.
• W2007145808 cites W66606103 @default.
• W2007145808 cites W970826558 @default.
• W2007145808 cites W104117918 @default.
• W2007145808 doi "https://doi.org/10.1371/journal.pone.0025980" @default.
• W2007145808 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3191173" @default.
• W2007145808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22022485" @default.
• W2007145808 hasPublicationYear "2011" @default.
• W2007145808 type Work @default.
• W2007145808 sameAs 2007145808 @default.
• W2007145808 citedByCount "56" @default.
• W2007145808 countsByYear W20071458082012 @default.
• W2007145808 countsByYear W20071458082013 @default.
• W2007145808 countsByYear W20071458082014 @default.
• W2007145808 countsByYear W20071458082015 @default.
• W2007145808 countsByYear W20071458082016 @default.
• W2007145808 countsByYear W20071458082017 @default.
• W2007145808 countsByYear W20071458082018 @default.
• W2007145808 countsByYear W20071458082019 @default.
• W2007145808 countsByYear W20071458082020 @default.
• W2007145808 countsByYear W20071458082021 @default.
• W2007145808 countsByYear W20071458082022 @default.
• W2007145808 countsByYear W20071458082023 @default.
• W2007145808 crossrefType "journal-article" @default.

• next