Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007156741> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2007156741 endingPage "612" @default.
- W2007156741 startingPage "607" @default.
- W2007156741 abstract "Four male Sprague-Dawley rats were trained to discriminate IP injections of 3.0 mg/kg phencyclidine (PCP) from saline under a 2-lever fixed-ratio 32 schedule of food presentation. After reliable discriminative control of lever choice was established, other doses of injected PCP were tested resulting in dose-dependent increases in PCP-lever selection and dose-dependent decreases in rates of responding. When doses of PCP were administered by exposure to smoke from cigarettes containing PCP, a dose-dependent increase in PCP-lever responding was also observed. delta 9-Tetrahydrocannabinol administered via smoke exposure, up to doses which markedly suppressed response rates, did not result in PCP-appropriate responding, demonstrating the specificity of the PCP stimulus by the inhalation route. Brain levels and distribution of 3H-PCP were determined in rats administered doses calculated to result in 50% generalization by the IP injection or smoke inhalation routes. By both routes of administration roughly equivalent brain levels were attained and the distribution was relatively even across the seven brain areas analyzed. These results demonstrate the validity of using the injection route of administration when studying PCP experimentally, in spite of the fact that PCP is abused primarily by smoking." @default.
- W2007156741 created "2016-06-24" @default.
- W2007156741 creator A5004540382 @default.
- W2007156741 creator A5046058649 @default.
- W2007156741 creator A5075600676 @default.
- W2007156741 date "1985-10-01" @default.
- W2007156741 modified "2023-10-14" @default.
- W2007156741 title "Discriminative stimulus properties and brain distribution of phencyclidine in rats following administration by injection and smoke inhalation" @default.
- W2007156741 cites W1684853394 @default.
- W2007156741 cites W1982299590 @default.
- W2007156741 cites W1986834206 @default.
- W2007156741 cites W1993832934 @default.
- W2007156741 cites W2003793455 @default.
- W2007156741 cites W2008858337 @default.
- W2007156741 cites W2019161686 @default.
- W2007156741 cites W2028548323 @default.
- W2007156741 cites W2059394174 @default.
- W2007156741 cites W2064767228 @default.
- W2007156741 cites W2070903143 @default.
- W2007156741 cites W2083161480 @default.
- W2007156741 cites W2125058598 @default.
- W2007156741 doi "https://doi.org/10.1016/0091-3057(85)90425-3" @default.
- W2007156741 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2999833" @default.
- W2007156741 hasPublicationYear "1985" @default.
- W2007156741 type Work @default.
- W2007156741 sameAs 2007156741 @default.
- W2007156741 citedByCount "8" @default.
- W2007156741 countsByYear W20071567412013 @default.
- W2007156741 countsByYear W20071567412016 @default.
- W2007156741 countsByYear W20071567412019 @default.
- W2007156741 crossrefType "journal-article" @default.
- W2007156741 hasAuthorship W2007156741A5004540382 @default.
- W2007156741 hasAuthorship W2007156741A5046058649 @default.
- W2007156741 hasAuthorship W2007156741A5075600676 @default.
- W2007156741 hasConcept C126322002 @default.
- W2007156741 hasConcept C15744967 @default.
- W2007156741 hasConcept C170493617 @default.
- W2007156741 hasConcept C2776954882 @default.
- W2007156741 hasConcept C2777397205 @default.
- W2007156741 hasConcept C2778851735 @default.
- W2007156741 hasConcept C2779547902 @default.
- W2007156741 hasConcept C2779918689 @default.
- W2007156741 hasConcept C2780871563 @default.
- W2007156741 hasConcept C2909767651 @default.
- W2007156741 hasConcept C42219234 @default.
- W2007156741 hasConcept C542102704 @default.
- W2007156741 hasConcept C57022672 @default.
- W2007156741 hasConcept C67018056 @default.
- W2007156741 hasConcept C71924100 @default.
- W2007156741 hasConcept C98274493 @default.
- W2007156741 hasConceptScore W2007156741C126322002 @default.
- W2007156741 hasConceptScore W2007156741C15744967 @default.
- W2007156741 hasConceptScore W2007156741C170493617 @default.
- W2007156741 hasConceptScore W2007156741C2776954882 @default.
- W2007156741 hasConceptScore W2007156741C2777397205 @default.
- W2007156741 hasConceptScore W2007156741C2778851735 @default.
- W2007156741 hasConceptScore W2007156741C2779547902 @default.
- W2007156741 hasConceptScore W2007156741C2779918689 @default.
- W2007156741 hasConceptScore W2007156741C2780871563 @default.
- W2007156741 hasConceptScore W2007156741C2909767651 @default.
- W2007156741 hasConceptScore W2007156741C42219234 @default.
- W2007156741 hasConceptScore W2007156741C542102704 @default.
- W2007156741 hasConceptScore W2007156741C57022672 @default.
- W2007156741 hasConceptScore W2007156741C67018056 @default.
- W2007156741 hasConceptScore W2007156741C71924100 @default.
- W2007156741 hasConceptScore W2007156741C98274493 @default.
- W2007156741 hasIssue "4" @default.
- W2007156741 hasLocation W20071567411 @default.
- W2007156741 hasLocation W20071567412 @default.
- W2007156741 hasOpenAccess W2007156741 @default.
- W2007156741 hasPrimaryLocation W20071567411 @default.
- W2007156741 hasRelatedWork W2014693564 @default.
- W2007156741 hasRelatedWork W2033905064 @default.
- W2007156741 hasRelatedWork W2064767228 @default.
- W2007156741 hasRelatedWork W2075146169 @default.
- W2007156741 hasRelatedWork W2075240784 @default.
- W2007156741 hasRelatedWork W2098260243 @default.
- W2007156741 hasRelatedWork W2124009088 @default.
- W2007156741 hasRelatedWork W2143653836 @default.
- W2007156741 hasRelatedWork W2499735368 @default.
- W2007156741 hasRelatedWork W2731422221 @default.
- W2007156741 hasVolume "23" @default.
- W2007156741 isParatext "false" @default.
- W2007156741 isRetracted "false" @default.
- W2007156741 magId "2007156741" @default.
- W2007156741 workType "article" @default.