FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007156955> ?p ?o ?g. }

• W2007156955 endingPage "136" @default.
• W2007156955 startingPage "131" @default.
• W2007156955 abstract "Voltage-dependent potassium currents play a key role in shaping the firing pattern of central neurons. Their pharmacological and physiological identification is rather important in the structures which are involved in the filtering of inputloutput messages. In this regard, globus pallidus external segment (GPe) is indicated as a crucial station in the well-known indirect pathway of the basal ganglia. Among the potassium conductances which have been indicated to condition the firing behavior and the neuronal integrative properties in many central neurons, we analysed the depolarization-activated ones by means of patchclamp recordings in the whole-cell configuration. Two main families of calcium-independent outward potassium currents are activated by depolarization in GPe neurons acutely isolated from the adult rat. From depolarized holding potentials (−50/−45 mV), a slowly-activating, sustained current is evoked; it manifests very little inactivation and it is available at rather depolarized potentials (−30 mV/−20 mV). This current is relatively resistant to 4-aminopyridine (4-AP)but it is blocked by tetraethilammonium ions (TEA) and consequently it resembles delayed rectifier current (Ik). From negative holding potentials (−8O/−lOO mV), on the other hand, A-like conductances are activated. Together with a fast-inactivating transient current, another component is observed in a significant proportion of recordings (45%). This current shows half-inactivation voltage around −90 mV, peculiar sensitivity to micromolar doses of 4-AF' and a slow rate of recovery from inactivation. The presence and the modulation of these A-like currents may be a very critical aspect in the membrane physiology of pallidal neurons. © 1995 Wiley-Liss, Inc." @default.
• W2007156955 created "2016-06-24" @default.
• W2007156955 creator A5021429755 @default.
• W2007156955 creator A5022210828 @default.
• W2007156955 creator A5031415079 @default.
• W2007156955 creator A5054830439 @default.
• W2007156955 creator A5082221123 @default.
• W2007156955 date "1995-06-01" @default.
• W2007156955 modified "2023-09-23" @default.
• W2007156955 title "Outward potassium currents activated by depolarization in rat globus pallidus" @default.
• W2007156955 cites W1780086468 @default.
• W2007156955 cites W1830737945 @default.
• W2007156955 cites W1972754730 @default.
• W2007156955 cites W1973941257 @default.
• W2007156955 cites W1976763631 @default.
• W2007156955 cites W2015317874 @default.
• W2007156955 cites W2019562175 @default.
• W2007156955 cites W2026608250 @default.
• W2007156955 cites W2037161069 @default.
• W2007156955 cites W2041629506 @default.
• W2007156955 cites W2045178139 @default.
• W2007156955 cites W2045979700 @default.
• W2007156955 cites W2077689888 @default.
• W2007156955 cites W2084259705 @default.
• W2007156955 cites W2087156861 @default.
• W2007156955 cites W2087989984 @default.
• W2007156955 cites W2118664845 @default.
• W2007156955 cites W2122946342 @default.
• W2007156955 cites W2168823834 @default.
• W2007156955 cites W2336720618 @default.
• W2007156955 cites W2345805812 @default.
• W2007156955 cites W2400616252 @default.
• W2007156955 cites W2413513126 @default.
• W2007156955 cites W2469351461 @default.
• W2007156955 doi "https://doi.org/10.1002/syn.890200206" @default.
• W2007156955 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7570342" @default.
• W2007156955 hasPublicationYear "1995" @default.
• W2007156955 type Work @default.
• W2007156955 sameAs 2007156955 @default.
• W2007156955 citedByCount "11" @default.
• W2007156955 countsByYear W20071569552015 @default.
• W2007156955 crossrefType "journal-article" @default.
• W2007156955 hasAuthorship W2007156955A5021429755 @default.
• W2007156955 hasAuthorship W2007156955A5022210828 @default.
• W2007156955 hasAuthorship W2007156955A5031415079 @default.
• W2007156955 hasAuthorship W2007156955A5054830439 @default.
• W2007156955 hasAuthorship W2007156955A5082221123 @default.
• W2007156955 hasConcept C101404756 @default.
• W2007156955 hasConcept C12554922 @default.
• W2007156955 hasConcept C147944092 @default.
• W2007156955 hasConcept C169760540 @default.
• W2007156955 hasConcept C178790620 @default.
• W2007156955 hasConcept C181911157 @default.
• W2007156955 hasConcept C185263204 @default.
• W2007156955 hasConcept C185592680 @default.
• W2007156955 hasConcept C2778187257 @default.
• W2007156955 hasConcept C2780278869 @default.
• W2007156955 hasConcept C2780922449 @default.
• W2007156955 hasConcept C4141045 @default.
• W2007156955 hasConcept C517785266 @default.
• W2007156955 hasConcept C529278444 @default.
• W2007156955 hasConcept C83743174 @default.
• W2007156955 hasConcept C86803240 @default.
• W2007156955 hasConceptScore W2007156955C101404756 @default.
• W2007156955 hasConceptScore W2007156955C12554922 @default.
• W2007156955 hasConceptScore W2007156955C147944092 @default.
• W2007156955 hasConceptScore W2007156955C169760540 @default.
• W2007156955 hasConceptScore W2007156955C178790620 @default.
• W2007156955 hasConceptScore W2007156955C181911157 @default.
• W2007156955 hasConceptScore W2007156955C185263204 @default.
• W2007156955 hasConceptScore W2007156955C185592680 @default.
• W2007156955 hasConceptScore W2007156955C2778187257 @default.
• W2007156955 hasConceptScore W2007156955C2780278869 @default.
• W2007156955 hasConceptScore W2007156955C2780922449 @default.
• W2007156955 hasConceptScore W2007156955C4141045 @default.
• W2007156955 hasConceptScore W2007156955C517785266 @default.
• W2007156955 hasConceptScore W2007156955C529278444 @default.
• W2007156955 hasConceptScore W2007156955C83743174 @default.
• W2007156955 hasConceptScore W2007156955C86803240 @default.
• W2007156955 hasIssue "2" @default.
• W2007156955 hasLocation W20071569551 @default.
• W2007156955 hasLocation W20071569552 @default.
• W2007156955 hasOpenAccess W2007156955 @default.
• W2007156955 hasPrimaryLocation W20071569551 @default.
• W2007156955 hasRelatedWork W111279135 @default.
• W2007156955 hasRelatedWork W1990054546 @default.
• W2007156955 hasRelatedWork W1994630059 @default.
• W2007156955 hasRelatedWork W1997560222 @default.
• W2007156955 hasRelatedWork W2008384579 @default.
• W2007156955 hasRelatedWork W2048011947 @default.
• W2007156955 hasRelatedWork W2055830121 @default.
• W2007156955 hasRelatedWork W2415407601 @default.
• W2007156955 hasRelatedWork W2463100686 @default.
• W2007156955 hasRelatedWork W2409558422 @default.
• W2007156955 hasVolume "20" @default.
• W2007156955 isParatext "false" @default.
• W2007156955 isRetracted "false" @default.
• W2007156955 magId "2007156955" @default.

• next