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- W2007176585 abstract "Les anticorps anticardiolipine, classiquement associés à des thromboses vasculaires au cours du lupus érythémateux, ont été récemment signalés au cours d'accidents vasculaires cérébraux chez l'enfant et d'hémorragies surrénaliennes chez l'adulte. Cas clinique. — Un nouveau-néà terme avait présenté au troisième jour de vie une ischémie cérébrale et une hémorragie surrénalienne massive. Des anticorps anticardiolipine avaient été détectés à la phase initiale el persistaient à l'âge de 7 mois. Il n'y avait pas de souffrance périnatale ni de pathologie maternelle connue; cependant, des anticorps anticardiolipine ont été trouvés chez la mère 5 et 15 semaines après l'accouchement. Conclusion. — L'association anticorps anticardiolipine et thromboses vasculaires n'a jamais été décrite en période néonatale. La persistance de ces anticorps plaide contre l'hypothèse de leur transmission maternofcetale; ils pourraient être le témoin précoce d un syndrome antiphospholipides primaire. Background. — Anticardiolipin antibodies, usually associated with vascular thrombosis in systemic lupus erythematosus, have been recently found associated with strokes in childhood, and acute adrenal hemorrhage in the adult. Case report. — A 3 day-old fullterm newborn suffering from cerebrovascular ischemia and bilateral massive hemorrhage was found to have anticardiolipin antibodies detected during the neonatal period and 7 months later. There was no evidence of pathology in the mother or perinatal asphyxia. However, anticardiolipin antibodies were present in the mother 5 and 15 weeks after delivery. Conclusion. — Association of anticardiolipin antibodies and vascular thrombosis has never been reported in the neonate. Persistence of such antibodies favor the hypothesis that they are not transmitted by the mother; they could represent an early manifestation of primary antiphospholipid syndrome." @default.
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- W2007176585 date "1995-11-01" @default.
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- W2007176585 title "Anticorps anticardiolipine, ischémie cérébrale et hémorragie surrénalienne chez un nouveau-né" @default.
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- W2007176585 doi "https://doi.org/10.1016/0929-693x(96)81285-1" @default.
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