Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007177026> ?p ?o ?g. }
- W2007177026 endingPage "4524" @default.
- W2007177026 startingPage "4517" @default.
- W2007177026 abstract "The formation of self-assembled monolayers (SAMs) of representative thiocarbohydrate derivatives onto a gold surface has been investigated to build an artificial carbohydrate scaffold to mimic non-bonded molecular recognition phenomena. Three types of carbohydrate SAMs were formulated from (i) 1-β-d-thioglucose (1), (ii) 1-β-d-thioglucose tetraacetate (2), and (iii) 2-mercaptoethyl α-d-mannopyranoside (3). Subsequently, each SAM was spectroscopically characterized by reflection-absorption infrared spectroscopy (RAIRS). Deprotection of the acylated carbohydrate SAM was achieved in situ, indicating that chemical transformation may be performed without disruption of the sulfurgold bond. With the mannose derivative, in which the carbohydrate moiety was separated from the gold surface by the spacer unit OCH2CH2SH, it was possible to demonstrate that such a carbohydrate SAM was able to interact selectively with a specific carbohydrate binding protein, i.e., concanavalin A (Con A). Exposure of the mannose derived SAM to a solution of Con A led to a specific binding interaction as measured by RAIRS and surface plasmon resonance (SPR). In contrast, on exposure of the mannose SAM to the l-fucose-specific lectin tetragonolobus purpureas, no such binding was observed. These results suggest that highly ordered SAMs of specifically designed carbohydrate derivatives can be formulated to mimic natural cell surface structures and used to study selective molecular recognition interactions." @default.
- W2007177026 created "2016-06-24" @default.
- W2007177026 creator A5010562141 @default.
- W2007177026 creator A5016156910 @default.
- W2007177026 creator A5052370496 @default.
- W2007177026 creator A5071073270 @default.
- W2007177026 creator A5072150707 @default.
- W2007177026 date "1998-07-17" @default.
- W2007177026 modified "2023-10-03" @default.
- W2007177026 title "Self-Assembled Carbohydrate Monolayers: Formation and Surface Selective Molecular Recognition" @default.
- W2007177026 cites W1264444877 @default.
- W2007177026 cites W1510740834 @default.
- W2007177026 cites W1778340992 @default.
- W2007177026 cites W1906831495 @default.
- W2007177026 cites W1965825251 @default.
- W2007177026 cites W1967598238 @default.
- W2007177026 cites W1973413026 @default.
- W2007177026 cites W1992034958 @default.
- W2007177026 cites W2007814605 @default.
- W2007177026 cites W2008965637 @default.
- W2007177026 cites W2009377140 @default.
- W2007177026 cites W2014362134 @default.
- W2007177026 cites W2024004515 @default.
- W2007177026 cites W2025612977 @default.
- W2007177026 cites W2030500690 @default.
- W2007177026 cites W2057026474 @default.
- W2007177026 cites W2057080539 @default.
- W2007177026 cites W2059842708 @default.
- W2007177026 cites W2089855429 @default.
- W2007177026 cites W2090106568 @default.
- W2007177026 cites W2090415116 @default.
- W2007177026 cites W2108425224 @default.
- W2007177026 cites W2129232972 @default.
- W2007177026 cites W2134819724 @default.
- W2007177026 cites W2169052834 @default.
- W2007177026 doi "https://doi.org/10.1021/la9802466" @default.
- W2007177026 hasPublicationYear "1998" @default.
- W2007177026 type Work @default.
- W2007177026 sameAs 2007177026 @default.
- W2007177026 citedByCount "93" @default.
- W2007177026 countsByYear W20071770262012 @default.
- W2007177026 countsByYear W20071770262013 @default.
- W2007177026 countsByYear W20071770262015 @default.
- W2007177026 countsByYear W20071770262017 @default.
- W2007177026 countsByYear W20071770262018 @default.
- W2007177026 countsByYear W20071770262019 @default.
- W2007177026 countsByYear W20071770262020 @default.
- W2007177026 countsByYear W20071770262021 @default.
- W2007177026 countsByYear W20071770262022 @default.
- W2007177026 crossrefType "journal-article" @default.
- W2007177026 hasAuthorship W2007177026A5010562141 @default.
- W2007177026 hasAuthorship W2007177026A5016156910 @default.
- W2007177026 hasAuthorship W2007177026A5052370496 @default.
- W2007177026 hasAuthorship W2007177026A5071073270 @default.
- W2007177026 hasAuthorship W2007177026A5072150707 @default.
- W2007177026 hasConcept C106847996 @default.
- W2007177026 hasConcept C131649739 @default.
- W2007177026 hasConcept C155672457 @default.
- W2007177026 hasConcept C171250308 @default.
- W2007177026 hasConcept C178790620 @default.
- W2007177026 hasConcept C179303850 @default.
- W2007177026 hasConcept C185592680 @default.
- W2007177026 hasConcept C192562407 @default.
- W2007177026 hasConcept C19869320 @default.
- W2007177026 hasConcept C202751555 @default.
- W2007177026 hasConcept C2775887612 @default.
- W2007177026 hasConcept C2778977261 @default.
- W2007177026 hasConcept C32909587 @default.
- W2007177026 hasConcept C55493867 @default.
- W2007177026 hasConcept C7070889 @default.
- W2007177026 hasConcept C71240020 @default.
- W2007177026 hasConceptScore W2007177026C106847996 @default.
- W2007177026 hasConceptScore W2007177026C131649739 @default.
- W2007177026 hasConceptScore W2007177026C155672457 @default.
- W2007177026 hasConceptScore W2007177026C171250308 @default.
- W2007177026 hasConceptScore W2007177026C178790620 @default.
- W2007177026 hasConceptScore W2007177026C179303850 @default.
- W2007177026 hasConceptScore W2007177026C185592680 @default.
- W2007177026 hasConceptScore W2007177026C192562407 @default.
- W2007177026 hasConceptScore W2007177026C19869320 @default.
- W2007177026 hasConceptScore W2007177026C202751555 @default.
- W2007177026 hasConceptScore W2007177026C2775887612 @default.
- W2007177026 hasConceptScore W2007177026C2778977261 @default.
- W2007177026 hasConceptScore W2007177026C32909587 @default.
- W2007177026 hasConceptScore W2007177026C55493867 @default.
- W2007177026 hasConceptScore W2007177026C7070889 @default.
- W2007177026 hasConceptScore W2007177026C71240020 @default.
- W2007177026 hasIssue "16" @default.
- W2007177026 hasLocation W20071770261 @default.
- W2007177026 hasOpenAccess W2007177026 @default.
- W2007177026 hasPrimaryLocation W20071770261 @default.
- W2007177026 hasRelatedWork W1505520335 @default.
- W2007177026 hasRelatedWork W2019880615 @default.
- W2007177026 hasRelatedWork W2025249748 @default.
- W2007177026 hasRelatedWork W2260714143 @default.
- W2007177026 hasRelatedWork W2316483535 @default.
- W2007177026 hasRelatedWork W2323010580 @default.
- W2007177026 hasRelatedWork W2578516552 @default.