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- W2007181946 abstract "The α-adrenoceptor agonist and antagonist actions of lisuride and other ergot derivatives were assessed in spleen strips ( α 1 -adrenoceptor) and transmurally stimulated ileal preparations ( α 2 -adrenoceptor) from the guinea-pig. The compounds tested were devoid of α-adrenoceptor agonistic activity, however many were selective α-adrenoceptor antagonists. Lisuride was α 2 -selective, having a pA 2 value of 9.70 in guinea-pig ileal and 7.47 in splenic preparations. Conversely, bromocriptine was α 1 -selective with a pA 2 of 7.46 in spleen strips; it had no measurable effect in the ileum." @default.
- W2007181946 created "2016-06-24" @default.
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- W2007181946 date "1984-01-01" @default.
- W2007181946 modified "2023-09-25" @default.
- W2007181946 title "In vitro selectivity of lisuride and other ergot derivatives for α1- and α2-adrenoceptors" @default.
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- W2007181946 doi "https://doi.org/10.1016/0014-2999(84)90525-9" @default.
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