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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007183775> ?p ?o ?g. }

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• W2007183775 abstract "While medical scientific knowledge pertaining to bacterial adhesion to biomaterials has become a rapidly growing field in most areas of medicine, its significance in ophthalmic infections has not been emphasized. Corneal bacterial ulceration in patients wearing extended-wear contact lenses has become a problem of epidemic proportions. The designation of the contact lens itself as a suitable substratum for bacterial colonization and as a source of subsequent inoculum to compromised epithelial cells are important factors in the pathophysiology of corneal ulcer formation. We demonstrate polysaccharide- (biofilm-)mediated adhesion to two ophthalmic pathogens (Pseudomonas aeruginosa and Staphylococcus epidermidis) to the surface of a typical extended-wear contact lens in vitro using cytochemistry and scanning and transmission electron microscopic techniques. This interaction between the biomaterial and bacterial organisms, which represents a favorable self-protective environment for propagation and inoculation, is a previously overlooked area of importance in the mechanism of corneal ulceration associated with hydrophilic (soft) contact lenses." @default.
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• W2007183775 date "1987-01-01" @default.
• W2007183775 modified "2023-10-16" @default.
• W2007183775 title "Extended-Wear Lenses, Biofilm, and Bacterial Adhesion" @default.
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• W2007183775 doi "https://doi.org/10.1001/archopht.1987.01060010116042" @default.
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