FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007185102> ?p ?o ?g. }

• W2007185102 endingPage "182" @default.
• W2007185102 startingPage "176" @default.
• W2007185102 abstract "GAP43 is a protein involved in neurite outgrowth during development and axon regeneration reflecting its presynaptic localization in developing neurons. Recently, it has been demonstrated that GAP43 is a ligand of CASP3 involved in receptor endocytosis and is also localized post-synaptically. In this study, by using a transgenic mouse strain carrying a bioluminescent reporter for GAP43 combined with an in vivo bioluminescence assay for CASP3, we demonstrated that one day after brain ischemic lesion and, even more pronounced, four days after stroke, expression of both CASP3 and Gap43 in neurons increased more than 40 times. The in vivo approach of CASP3 and GAP43 colocalization imaging was further validated and quantified by immunofluorescence. Importantly, in 82% of GAP43 positive cells, colocalization with CASP3 was present. These findings suggested that one and four days after stroke CASP3 expression, not necessarily associated with neuronal death, increased and suggested that CASP3 and GAP43 might be part of a common molecular pathway involved in early response to ischemic events occurring after onset of stroke." @default.
• W2007185102 created "2016-06-24" @default.
• W2007185102 creator A5020540455 @default.
• W2007185102 creator A5024493112 @default.
• W2007185102 creator A5025245039 @default.
• W2007185102 creator A5026081869 @default.
• W2007185102 creator A5057957918 @default.
• W2007185102 creator A5063701490 @default.
• W2007185102 creator A5082354065 @default.
• W2007185102 date "2015-06-01" @default.
• W2007185102 modified "2023-10-06" @default.
• W2007185102 title "Increased expression and colocalization of GAP43 and CASP3 after brain ischemic lesion in mouse" @default.
• W2007185102 cites W1631059898 @default.
• W2007185102 cites W1979485742 @default.
• W2007185102 cites W1996687999 @default.
• W2007185102 cites W1997912239 @default.
• W2007185102 cites W2004002339 @default.
• W2007185102 cites W2006413689 @default.
• W2007185102 cites W2037390002 @default.
• W2007185102 cites W2045669555 @default.
• W2007185102 cites W2046297960 @default.
• W2007185102 cites W2048836779 @default.
• W2007185102 cites W2049201207 @default.
• W2007185102 cites W2056424069 @default.
• W2007185102 cites W2056889971 @default.
• W2007185102 cites W2070342845 @default.
• W2007185102 cites W2082847466 @default.
• W2007185102 cites W2112476462 @default.
• W2007185102 cites W2114381143 @default.
• W2007185102 cites W2124551632 @default.
• W2007185102 cites W2167820114 @default.
• W2007185102 doi "https://doi.org/10.1016/j.neulet.2015.04.042" @default.
• W2007185102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25929184" @default.
• W2007185102 hasPublicationYear "2015" @default.
• W2007185102 type Work @default.
• W2007185102 sameAs 2007185102 @default.
• W2007185102 citedByCount "42" @default.
• W2007185102 countsByYear W20071851022016 @default.
• W2007185102 countsByYear W20071851022017 @default.
• W2007185102 countsByYear W20071851022018 @default.
• W2007185102 countsByYear W20071851022019 @default.
• W2007185102 countsByYear W20071851022020 @default.
• W2007185102 countsByYear W20071851022021 @default.
• W2007185102 countsByYear W20071851022022 @default.
• W2007185102 countsByYear W20071851022023 @default.
• W2007185102 crossrefType "journal-article" @default.
• W2007185102 hasAuthorship W2007185102A5020540455 @default.
• W2007185102 hasAuthorship W2007185102A5024493112 @default.
• W2007185102 hasAuthorship W2007185102A5025245039 @default.
• W2007185102 hasAuthorship W2007185102A5026081869 @default.
• W2007185102 hasAuthorship W2007185102A5057957918 @default.
• W2007185102 hasAuthorship W2007185102A5063701490 @default.
• W2007185102 hasAuthorship W2007185102A5082354065 @default.
• W2007185102 hasBestOaLocation W20071851021 @default.
• W2007185102 hasConcept C113246987 @default.
• W2007185102 hasConcept C142724271 @default.
• W2007185102 hasConcept C150903083 @default.
• W2007185102 hasConcept C159654299 @default.
• W2007185102 hasConcept C169760540 @default.
• W2007185102 hasConcept C173396325 @default.
• W2007185102 hasConcept C190283241 @default.
• W2007185102 hasConcept C202751555 @default.
• W2007185102 hasConcept C203014093 @default.
• W2007185102 hasConcept C204232928 @default.
• W2007185102 hasConcept C207001950 @default.
• W2007185102 hasConcept C2778236600 @default.
• W2007185102 hasConcept C2779530196 @default.
• W2007185102 hasConcept C40209533 @default.
• W2007185102 hasConcept C55493867 @default.
• W2007185102 hasConcept C71924100 @default.
• W2007185102 hasConcept C86803240 @default.
• W2007185102 hasConcept C90770895 @default.
• W2007185102 hasConcept C95444343 @default.
• W2007185102 hasConceptScore W2007185102C113246987 @default.
• W2007185102 hasConceptScore W2007185102C142724271 @default.
• W2007185102 hasConceptScore W2007185102C150903083 @default.
• W2007185102 hasConceptScore W2007185102C159654299 @default.
• W2007185102 hasConceptScore W2007185102C169760540 @default.
• W2007185102 hasConceptScore W2007185102C173396325 @default.
• W2007185102 hasConceptScore W2007185102C190283241 @default.
• W2007185102 hasConceptScore W2007185102C202751555 @default.
• W2007185102 hasConceptScore W2007185102C203014093 @default.
• W2007185102 hasConceptScore W2007185102C204232928 @default.
• W2007185102 hasConceptScore W2007185102C207001950 @default.
• W2007185102 hasConceptScore W2007185102C2778236600 @default.
• W2007185102 hasConceptScore W2007185102C2779530196 @default.
• W2007185102 hasConceptScore W2007185102C40209533 @default.
• W2007185102 hasConceptScore W2007185102C55493867 @default.
• W2007185102 hasConceptScore W2007185102C71924100 @default.
• W2007185102 hasConceptScore W2007185102C86803240 @default.
• W2007185102 hasConceptScore W2007185102C90770895 @default.
• W2007185102 hasConceptScore W2007185102C95444343 @default.
• W2007185102 hasLocation W20071851021 @default.
• W2007185102 hasLocation W20071851022 @default.
• W2007185102 hasLocation W20071851023 @default.
• W2007185102 hasOpenAccess W2007185102 @default.
• W2007185102 hasPrimaryLocation W20071851021 @default.
• W2007185102 hasRelatedWork W2007141251 @default.

• next