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- W2007189341 abstract "The use of the simplex procedure as a non-linear least-squares curve-fitting method is proposed for evaluation of equivalence points in sigmoidal and segmented titration curves. The application of this procedure to theoretical curves affected by different amounts of random noise indicates its effectiveness and accuracy for locating the correct end-point in titrations characterized by very low reaction constants. The relevant results are compared with those obtained by other regression methods as well as by the first-derivative and Gran approaches." @default.
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- W2007189341 date "1986-01-01" @default.
- W2007189341 modified "2023-09-26" @default.
- W2007189341 title "Simplex optimization procedure for evaluating equivalence points in sigmoidal and segmented titration curves" @default.
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- W2007189341 doi "https://doi.org/10.1016/s0003-2670(00)86323-0" @default.
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