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• W2007193648 abstract "OBJECTIVES The purpose of this study was to identify trends and factors associated with outcomes of persistent truncus arteriosus (PTA). BACKGROUND Although there have been significant improvements, PTA continues to be associated with significant morbidity and mortality. METHODS We undertook a review of all consecutive cases of PTA (n = 205) presenting at our institution from 1953 to 1997. Data were collected regarding demographics, anatomy, management (surgical palliation and repair) and outcomes (mortality and reoperation). RESULTS Significant trends (p ≤ 0.001) related to groups defined by year of birth were as follows: number of cases (1953–1967, n = 13; 1968–1977, n = 42; 1978–1987, n = 69; 1988–1997, n = 81), median age at first assessment (8 months, 42 days, 7 days and 2 days, respectively), proportion who did not have any surgery (58%, 27%, 22% and 11%), proportion who had an initial palliative procedure (25%, 37%, 6% and 2%), proportion who underwent PTA repair (31%, 59%, 72% and 88%), median age at PTA repair (11.2 years, 1.1 years, 1.6 months and 12 days) and proportion dying before hospital discharge after repair (50%, 63%, 56% and 41%). Since 1995, mortality before hospital discharge after repair has further decreased to 2/11 (18%). Increasing time to initial conduit replacement in hospital survivors was significantly related to larger sized conduit at repair (p = 0.02) and use of pulmonary homografts (vs. aortic homografts or xenografts; p = 0.002). Interventional catheterization to address conduit obstructions significantly increased conduit longevity. CONCLUSIONS Significant improvements in PTA outcomes are evident with trends toward earlier age at assessment and complete repair." @default.
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• W2007193648 date "1999-08-01" @default.
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• W2007193648 title "Factors associated with outcomes of persistent truncus arteriosus" @default.
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• W2007193648 doi "https://doi.org/10.1016/s0735-1097(99)00227-2" @default.
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