Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007205613> ?p ?o ?g. }
- W2007205613 endingPage "182" @default.
- W2007205613 startingPage "176" @default.
- W2007205613 abstract "Several human normal and neoplastic cell lines were screened for production of PDGF receptor competing activity. Conditioned medium from two sarcomas and one glioma blocked 125I-PDGF binding to human foreskin fibroblasts in a dose-dependent manner. In each case this effect was abolished when the conditioned medium was pretreated with PDGF-antiserum, indicating that the receptor competing activity was immunologically related to PDGF. Direct evidence for de novo synthesis of a PDGF-like component in the cultures was afforded by 35S-cysteine labeling of the three cell lines, followed by immunoprecipitation with PDGF antiserum. This resulted in the specific precipitation of a 31,000 molecular weight labeled protein, which upon reduction was split into two polypeptides of molecular weights 17,000 and 16,500. The significance of these findings in view of the recently discovered structure homology between PDGF and the transforming gene product of simian sarcoma virus, p28sis, is discussed." @default.
- W2007205613 created "2016-06-24" @default.
- W2007205613 creator A5022948168 @default.
- W2007205613 creator A5025337265 @default.
- W2007205613 creator A5035824635 @default.
- W2007205613 creator A5051005847 @default.
- W2007205613 creator A5084535456 @default.
- W2007205613 creator A5090354704 @default.
- W2007205613 date "1983-11-01" @default.
- W2007205613 modified "2023-10-17" @default.
- W2007205613 title "Synthesis of a PDGF-like growth factor in human glioma and sarcoma cells suggests the expression of the cellular homologue to the transforming protein of simian sarcoma virus" @default.
- W2007205613 cites W1464779590 @default.
- W2007205613 cites W1519494647 @default.
- W2007205613 cites W1543283875 @default.
- W2007205613 cites W1968911040 @default.
- W2007205613 cites W1982020713 @default.
- W2007205613 cites W1983041452 @default.
- W2007205613 cites W1989009382 @default.
- W2007205613 cites W1992280915 @default.
- W2007205613 cites W2011857798 @default.
- W2007205613 cites W2013911067 @default.
- W2007205613 cites W2018437033 @default.
- W2007205613 cites W2019663874 @default.
- W2007205613 cites W2020231800 @default.
- W2007205613 cites W2025529909 @default.
- W2007205613 cites W2035913563 @default.
- W2007205613 cites W2043144746 @default.
- W2007205613 cites W2057780760 @default.
- W2007205613 cites W2065004493 @default.
- W2007205613 cites W2069189914 @default.
- W2007205613 cites W2072054054 @default.
- W2007205613 cites W2083690533 @default.
- W2007205613 cites W2102838769 @default.
- W2007205613 cites W2117079180 @default.
- W2007205613 cites W2146923243 @default.
- W2007205613 cites W2180795626 @default.
- W2007205613 doi "https://doi.org/10.1016/0006-291x(83)91557-7" @default.
- W2007205613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6318746" @default.
- W2007205613 hasPublicationYear "1983" @default.
- W2007205613 type Work @default.
- W2007205613 sameAs 2007205613 @default.
- W2007205613 citedByCount "111" @default.
- W2007205613 crossrefType "journal-article" @default.
- W2007205613 hasAuthorship W2007205613A5022948168 @default.
- W2007205613 hasAuthorship W2007205613A5025337265 @default.
- W2007205613 hasAuthorship W2007205613A5035824635 @default.
- W2007205613 hasAuthorship W2007205613A5051005847 @default.
- W2007205613 hasAuthorship W2007205613A5084535456 @default.
- W2007205613 hasAuthorship W2007205613A5090354704 @default.
- W2007205613 hasConcept C104317684 @default.
- W2007205613 hasConcept C142724271 @default.
- W2007205613 hasConcept C147483822 @default.
- W2007205613 hasConcept C150194340 @default.
- W2007205613 hasConcept C153911025 @default.
- W2007205613 hasConcept C159047783 @default.
- W2007205613 hasConcept C170493617 @default.
- W2007205613 hasConcept C180361614 @default.
- W2007205613 hasConcept C195286587 @default.
- W2007205613 hasConcept C203014093 @default.
- W2007205613 hasConcept C2775960820 @default.
- W2007205613 hasConcept C2778256501 @default.
- W2007205613 hasConcept C2781294074 @default.
- W2007205613 hasConcept C502942594 @default.
- W2007205613 hasConcept C54355233 @default.
- W2007205613 hasConcept C55493867 @default.
- W2007205613 hasConcept C71829478 @default.
- W2007205613 hasConcept C71924100 @default.
- W2007205613 hasConcept C81885089 @default.
- W2007205613 hasConcept C86803240 @default.
- W2007205613 hasConcept C91523082 @default.
- W2007205613 hasConcept C95444343 @default.
- W2007205613 hasConceptScore W2007205613C104317684 @default.
- W2007205613 hasConceptScore W2007205613C142724271 @default.
- W2007205613 hasConceptScore W2007205613C147483822 @default.
- W2007205613 hasConceptScore W2007205613C150194340 @default.
- W2007205613 hasConceptScore W2007205613C153911025 @default.
- W2007205613 hasConceptScore W2007205613C159047783 @default.
- W2007205613 hasConceptScore W2007205613C170493617 @default.
- W2007205613 hasConceptScore W2007205613C180361614 @default.
- W2007205613 hasConceptScore W2007205613C195286587 @default.
- W2007205613 hasConceptScore W2007205613C203014093 @default.
- W2007205613 hasConceptScore W2007205613C2775960820 @default.
- W2007205613 hasConceptScore W2007205613C2778256501 @default.
- W2007205613 hasConceptScore W2007205613C2781294074 @default.
- W2007205613 hasConceptScore W2007205613C502942594 @default.
- W2007205613 hasConceptScore W2007205613C54355233 @default.
- W2007205613 hasConceptScore W2007205613C55493867 @default.
- W2007205613 hasConceptScore W2007205613C71829478 @default.
- W2007205613 hasConceptScore W2007205613C71924100 @default.
- W2007205613 hasConceptScore W2007205613C81885089 @default.
- W2007205613 hasConceptScore W2007205613C86803240 @default.
- W2007205613 hasConceptScore W2007205613C91523082 @default.
- W2007205613 hasConceptScore W2007205613C95444343 @default.
- W2007205613 hasIssue "1" @default.
- W2007205613 hasLocation W20072056131 @default.
- W2007205613 hasLocation W20072056132 @default.
- W2007205613 hasOpenAccess W2007205613 @default.
- W2007205613 hasPrimaryLocation W20072056131 @default.