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- W2007214191 abstract "This paper presents the review of the methods used in research of the biological active substances hydrophobicity, a very important property. The biological activity of some substances depends on their pharmacokinetics and pharmacodynamics. These processes depend on the molecule's capability to interact with two different media: aqueous (cells interior) and non-aqueous (cells membrane), or on the molecule lipophilicity. Today, great attention is given to investigation and systematic determination of drugs lipophilicity. In these researches chromatography methods have an important role." @default.
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- W2007214191 date "2009-01-01" @default.
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- W2007214191 title "Chromatography methods in investigation of lipophilicity of the biological active substances" @default.
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- W2007214191 doi "https://doi.org/10.2298/hemind0901033o" @default.
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