Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007218594> ?p ?o ?g. }
- W2007218594 endingPage "e1000011" @default.
- W2007218594 startingPage "e1000011" @default.
- W2007218594 abstract "Human remodeling and spacing factor (RSF) consists of a heterodimer of Rsf-1 and hSNF2H, a counterpart of Drosophila ISWI. RSF possesses not only chromatin remodeling activity but also chromatin assembly activity in vitro. While no other single factor can execute the same activities as RSF, the biological significance of RSF remained unknown. To investigate the in vivo function of RSF, we generated a mutant allele of Drosophila Rsf-1 (dRsf-1). The dRsf-1 mutant behaved as a dominant suppressor of position effect variegation. In dRsf-1 mutant, the levels of histone H3K9 dimethylation and histone H2A variant H2Av were significantly reduced in an euchromatic region juxtaposed with heterochromatin. Furthermore, using both genetic and biochemical approaches, we demonstrate that dRsf-1 interacts with H2Av and the H2Av-exchanging machinery Tip60 complex. These results suggest that RSF contributes to histone H2Av replacement in the pathway of silent chromatin formation." @default.
- W2007218594 created "2016-06-24" @default.
- W2007218594 creator A5003477447 @default.
- W2007218594 creator A5011762957 @default.
- W2007218594 creator A5012073590 @default.
- W2007218594 creator A5073346262 @default.
- W2007218594 creator A5078140561 @default.
- W2007218594 date "2008-02-29" @default.
- W2007218594 modified "2023-10-02" @default.
- W2007218594 title "RSF Governs Silent Chromatin Formation via Histone H2Av Replacement" @default.
- W2007218594 cites W1660332899 @default.
- W2007218594 cites W1841379276 @default.
- W2007218594 cites W1959228133 @default.
- W2007218594 cites W1969114671 @default.
- W2007218594 cites W1974227032 @default.
- W2007218594 cites W1977387171 @default.
- W2007218594 cites W1978569157 @default.
- W2007218594 cites W1987020026 @default.
- W2007218594 cites W1991685938 @default.
- W2007218594 cites W1994577866 @default.
- W2007218594 cites W1996287615 @default.
- W2007218594 cites W2006149421 @default.
- W2007218594 cites W2008308209 @default.
- W2007218594 cites W2010730368 @default.
- W2007218594 cites W2011807809 @default.
- W2007218594 cites W2015697863 @default.
- W2007218594 cites W2018420071 @default.
- W2007218594 cites W2026377072 @default.
- W2007218594 cites W2029388127 @default.
- W2007218594 cites W2030508892 @default.
- W2007218594 cites W2030653070 @default.
- W2007218594 cites W2033851204 @default.
- W2007218594 cites W2039597909 @default.
- W2007218594 cites W2042966777 @default.
- W2007218594 cites W2044495919 @default.
- W2007218594 cites W2047384517 @default.
- W2007218594 cites W2052100373 @default.
- W2007218594 cites W2054600961 @default.
- W2007218594 cites W2067583299 @default.
- W2007218594 cites W2070312499 @default.
- W2007218594 cites W2081032844 @default.
- W2007218594 cites W2084388180 @default.
- W2007218594 cites W2086574165 @default.
- W2007218594 cites W2092668333 @default.
- W2007218594 cites W2092797711 @default.
- W2007218594 cites W2100649212 @default.
- W2007218594 cites W2100770110 @default.
- W2007218594 cites W2102901123 @default.
- W2007218594 cites W2103660187 @default.
- W2007218594 cites W2106900737 @default.
- W2007218594 cites W2115275056 @default.
- W2007218594 cites W2124586087 @default.
- W2007218594 cites W2124732880 @default.
- W2007218594 cites W2127528497 @default.
- W2007218594 cites W2130562212 @default.
- W2007218594 cites W2132692201 @default.
- W2007218594 cites W2135232391 @default.
- W2007218594 cites W2143658931 @default.
- W2007218594 cites W2144746162 @default.
- W2007218594 cites W2144792857 @default.
- W2007218594 cites W2152531069 @default.
- W2007218594 cites W2155749206 @default.
- W2007218594 cites W2157002105 @default.
- W2007218594 cites W2160345231 @default.
- W2007218594 cites W2162811733 @default.
- W2007218594 cites W2162958692 @default.
- W2007218594 cites W2163591068 @default.
- W2007218594 doi "https://doi.org/10.1371/journal.pgen.1000011" @default.
- W2007218594 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2265536" @default.
- W2007218594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18454204" @default.
- W2007218594 hasPublicationYear "2008" @default.
- W2007218594 type Work @default.
- W2007218594 sameAs 2007218594 @default.
- W2007218594 citedByCount "60" @default.
- W2007218594 countsByYear W20072185942012 @default.
- W2007218594 countsByYear W20072185942013 @default.
- W2007218594 countsByYear W20072185942014 @default.
- W2007218594 countsByYear W20072185942015 @default.
- W2007218594 countsByYear W20072185942016 @default.
- W2007218594 countsByYear W20072185942017 @default.
- W2007218594 countsByYear W20072185942018 @default.
- W2007218594 countsByYear W20072185942019 @default.
- W2007218594 countsByYear W20072185942020 @default.
- W2007218594 countsByYear W20072185942021 @default.
- W2007218594 countsByYear W20072185942023 @default.
- W2007218594 crossrefType "journal-article" @default.
- W2007218594 hasAuthorship W2007218594A5003477447 @default.
- W2007218594 hasAuthorship W2007218594A5011762957 @default.
- W2007218594 hasAuthorship W2007218594A5012073590 @default.
- W2007218594 hasAuthorship W2007218594A5073346262 @default.
- W2007218594 hasAuthorship W2007218594A5078140561 @default.
- W2007218594 hasBestOaLocation W20072185941 @default.
- W2007218594 hasConcept C10058791 @default.
- W2007218594 hasConcept C100924687 @default.
- W2007218594 hasConcept C103435993 @default.
- W2007218594 hasConcept C104317684 @default.
- W2007218594 hasConcept C143065580 @default.
- W2007218594 hasConcept C153911025 @default.