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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007223417> ?p ?o ?g. }

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• W2007223417 abstract "We have developed a defined system to characterize the role of SR proteins and exonic enhancers in directly promoting splice-site interactions across an intron. Using RNA affinity chromatography, we find that SR proteins alone are sufficient to promote the specific association of the enhancer-containing exon 5 with the adjoining exon 6 from avian cardiac troponin-T. Direct visualization of this exon/exon association by electron spectroscopic imaging shows it to be highly specific. Furthermore, using in vivo characterized mutants of exon 5, we also show that this exon/exon association depends on the splicing enhancer within exon 5. These results suggest a model by which SR proteins may function through exonic enhancers to directly promote exon bridging." @default.
• W2007223417 created "2016-06-24" @default.
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• W2007223417 date "1998-03-03" @default.
• W2007223417 modified "2023-09-30" @default.
• W2007223417 title "SR proteins are sufficient for exon bridging across an intron" @default.
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• W2007223417 doi "https://doi.org/10.1073/pnas.95.5.2163" @default.
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