Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007230092> ?p ?o ?g. }
- W2007230092 endingPage "137" @default.
- W2007230092 startingPage "133" @default.
- W2007230092 abstract "The aim of this study was to determine whether there have been any significant changes in the demographics and perioperative care of FIGO stage IA(2)/IB(1) cervical cancer over the past 16 years and, if so, to quantify them.Since July 1984, all patients with FIGO stage IA(2)/IB(1) cervical cancer undergoing radical surgery by members of our division have been entered into a prospective database. Selection for surgery has been unchanged over the past 16 years. Since March 1994 and November 1996, one surgeon has performed radical vaginal trachelectomy and laparoscopic assisted radical vaginal hysterectomy, respectively. Statistical analysis used Spearman's correlation analysis, the proportional hazards regression model of Cox, and the Mantel-Hanzel test was performed. Due to the number of statistical analyses, statistical significance was defined as P < 0.01.Eight hundred sixty-four patients have undergone radical surgery (784 radical hysterectomy, 42 radical vaginal trachelectomy, 32 radical vaginal hysterectomy, 6 radical abdominal trachelectomy) for FIGO stage IA(2)/IB(1) carcinoma of the cervix by members of our division since 1984. There have been no changes in the median age (40 years), tumor size (2.0 cm), incidence of capillary lymphatic space involvement (47%), or positive pelvic lymph nodes (6%) over the past 16 years. The median Quetelet index (24.6), depth of tumor invasion (squamous cell carcinomas only) (6.0 mm), and proportion of patients with comorbid conditions (17%) have increased over time (P = 0.001, P = 0.003, and P < 0.001, respectively). Pathologically, there has been an increase in the proportion of adenocarcinomas (28%) and a decrease in the proportion of grade 3 tumors (28%) (P < 0.001 and P < 0.001, respectively). The median operating time (2.8 h), hospital stay (7.0 days), blood loss (600 cc), allogeneic blood transfusion (23%), postoperative infections (13%), and noninfectious complications (6%) have all decreased (P < 0.001, P < 0.001, P < 0.001, P < 0.001, P < 0.001, and P = 0.002, respectively). There has been no change in the incidence of positive surgical margins (3%), adjuvant radiation (13%), or recurrence-free survival (2 and 5 years, 94 and 90%, respectively) after a median follow-up of 45 months.Despite no substantive changes in the selection criteria for surgery and the small time interval studied (16 years), almost all indices of operative and postoperative morbidity analyzed have decreased significantly. These changes have occurred without an increase in the use of adjuvant radiation or decrease in recurrence-free survival. Although little progress has been made in the cure rates associated with surgical management of FIGO stage IA(2)/IB(1) cervical cancer during this time interval, it appears that the morbidity of surgery has decreased." @default.
- W2007230092 created "2016-06-24" @default.
- W2007230092 creator A5004021842 @default.
- W2007230092 creator A5005275599 @default.
- W2007230092 creator A5013567512 @default.
- W2007230092 creator A5018586121 @default.
- W2007230092 creator A5025929155 @default.
- W2007230092 creator A5057738047 @default.
- W2007230092 creator A5058396685 @default.
- W2007230092 creator A5063157771 @default.
- W2007230092 creator A5071539254 @default.
- W2007230092 date "2001-05-01" @default.
- W2007230092 modified "2023-09-26" @default.
- W2007230092 title "Changes in the Demographics and Perioperative Care of Stage IA2/IB1 Cervical Cancer over the Past 16 Years" @default.
- W2007230092 cites W1507966607 @default.
- W2007230092 cites W1581629818 @default.
- W2007230092 cites W1597754921 @default.
- W2007230092 cites W1970270617 @default.
- W2007230092 cites W1991250143 @default.
- W2007230092 cites W2000381781 @default.
- W2007230092 cites W2036320180 @default.
- W2007230092 cites W2054221737 @default.
- W2007230092 cites W2059800731 @default.
- W2007230092 cites W2070789376 @default.
- W2007230092 cites W2071650011 @default.
- W2007230092 cites W2078946935 @default.
- W2007230092 cites W2092729989 @default.
- W2007230092 cites W2092768624 @default.
- W2007230092 cites W2332127269 @default.
- W2007230092 cites W4293241248 @default.
- W2007230092 cites W4375845032 @default.
- W2007230092 doi "https://doi.org/10.1006/gyno.2001.6158" @default.
- W2007230092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11330939" @default.
- W2007230092 hasPublicationYear "2001" @default.
- W2007230092 type Work @default.
- W2007230092 sameAs 2007230092 @default.
- W2007230092 citedByCount "109" @default.
- W2007230092 countsByYear W20072300922012 @default.
- W2007230092 countsByYear W20072300922013 @default.
- W2007230092 countsByYear W20072300922014 @default.
- W2007230092 countsByYear W20072300922015 @default.
- W2007230092 countsByYear W20072300922016 @default.
- W2007230092 countsByYear W20072300922017 @default.
- W2007230092 countsByYear W20072300922018 @default.
- W2007230092 countsByYear W20072300922019 @default.
- W2007230092 countsByYear W20072300922020 @default.
- W2007230092 countsByYear W20072300922021 @default.
- W2007230092 countsByYear W20072300922022 @default.
- W2007230092 countsByYear W20072300922023 @default.
- W2007230092 crossrefType "journal-article" @default.
- W2007230092 hasAuthorship W2007230092A5004021842 @default.
- W2007230092 hasAuthorship W2007230092A5005275599 @default.
- W2007230092 hasAuthorship W2007230092A5013567512 @default.
- W2007230092 hasAuthorship W2007230092A5018586121 @default.
- W2007230092 hasAuthorship W2007230092A5025929155 @default.
- W2007230092 hasAuthorship W2007230092A5057738047 @default.
- W2007230092 hasAuthorship W2007230092A5058396685 @default.
- W2007230092 hasAuthorship W2007230092A5063157771 @default.
- W2007230092 hasAuthorship W2007230092A5071539254 @default.
- W2007230092 hasConcept C120665830 @default.
- W2007230092 hasConcept C121332964 @default.
- W2007230092 hasConcept C121608353 @default.
- W2007230092 hasConcept C126322002 @default.
- W2007230092 hasConcept C126894567 @default.
- W2007230092 hasConcept C131872663 @default.
- W2007230092 hasConcept C141071460 @default.
- W2007230092 hasConcept C146357865 @default.
- W2007230092 hasConcept C151730666 @default.
- W2007230092 hasConcept C2776874909 @default.
- W2007230092 hasConcept C2777740455 @default.
- W2007230092 hasConcept C2778220009 @default.
- W2007230092 hasConcept C2779494336 @default.
- W2007230092 hasConcept C2908921296 @default.
- W2007230092 hasConcept C2910227796 @default.
- W2007230092 hasConcept C29456083 @default.
- W2007230092 hasConcept C31174226 @default.
- W2007230092 hasConcept C50382708 @default.
- W2007230092 hasConcept C61511704 @default.
- W2007230092 hasConcept C65409693 @default.
- W2007230092 hasConcept C71924100 @default.
- W2007230092 hasConcept C86803240 @default.
- W2007230092 hasConceptScore W2007230092C120665830 @default.
- W2007230092 hasConceptScore W2007230092C121332964 @default.
- W2007230092 hasConceptScore W2007230092C121608353 @default.
- W2007230092 hasConceptScore W2007230092C126322002 @default.
- W2007230092 hasConceptScore W2007230092C126894567 @default.
- W2007230092 hasConceptScore W2007230092C131872663 @default.
- W2007230092 hasConceptScore W2007230092C141071460 @default.
- W2007230092 hasConceptScore W2007230092C146357865 @default.
- W2007230092 hasConceptScore W2007230092C151730666 @default.
- W2007230092 hasConceptScore W2007230092C2776874909 @default.
- W2007230092 hasConceptScore W2007230092C2777740455 @default.
- W2007230092 hasConceptScore W2007230092C2778220009 @default.
- W2007230092 hasConceptScore W2007230092C2779494336 @default.
- W2007230092 hasConceptScore W2007230092C2908921296 @default.
- W2007230092 hasConceptScore W2007230092C2910227796 @default.
- W2007230092 hasConceptScore W2007230092C29456083 @default.
- W2007230092 hasConceptScore W2007230092C31174226 @default.