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- W2007231531 abstract "The proband in this study had multiple congenital malformations and a constitutional 46,XY,-13, + der(13),t(13;15)(q34;q23)mat chromosome complement. A bone marrow aspirate revealed neuroblastoma, and cytogenetic studies on tumor cells revealed, in addition to the partial trisomy #15 and probable partial monosomy #13, hypotetraploidy with a mean chromosome number of 82-84, including 3 or 4 copies of each autosome, 2 X chromosomes, no Y chromosome, and a marker. Translocations involving chromosomes #1, #2, #3, #7, and #14 were present, along with multiple double minutes. The possibility that the inherited partial trisomy #15 (and/or partial chromosome #13 monosomy) predisposed to neuroblastoma and additional chromosome changes in this tumor is discussed." @default.
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- W2007231531 date "1984-02-01" @default.
- W2007231531 modified "2023-09-25" @default.
- W2007231531 title "Inherited partial trisomy #15 complicated by neuroblastoma" @default.
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- W2007231531 doi "https://doi.org/10.1016/0165-4608(84)90109-2" @default.
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