FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007236571> ?p ?o ?g. }

• W2007236571 endingPage "305" @default.
• W2007236571 startingPage "298" @default.
• W2007236571 abstract "Serotonin transporter (SERT, 5-HTT) is a key element in the serotonergic system which is probably involved in the psychiatric disorders commonly observed in people living with HIV/AIDS. However, no information is available about the effects of HIV infection on SERT expression. In this study, a TaqMan® real-time RT-PCR method was established, levels of SERT mRNA in the peripheral blood mononuclear cells (PBMCs) and various tissues from normal Chinese rhesus macaques, in PBMCs from 32 SHIV-sf162p4 infected rhesus macaques and from 8 rhesus macaques before and 7, 14, 21, 28 and 196 days after SHIV-sf162p4 infection, and in PBMCs before and after in vitro phytohemagglutinin (PHA) stimulation were examined. It was found that SERT mRNA was widely distributed in lymphoid tissues; the level of SERT mRNA was significantly reduced in PBMCs from SHIV infected rhesus macaques and in PBMCs stimulated with PHA. The most evident decrease (to about one-tenth) in SERT mRNA level was observed at day 7 after SHIV infection. Difference in PBMC SERT mRNA level between 5-HTTLPR genotypes was not statistically significant. These data indicated that, in addition to previously observed abnormality in serotonin metabolism, SERT expression might be affected in HIV/AIDS, which might be associated with depression and other psychiatric disorders in HIV/AIDS. Besides, this study provided a basis for quantitative analysis of SERT gene expression under effects of host and environmental factors, such as 5-HTTLPR genotypes, SERT targeting drugs or other infectious agents." @default.
• W2007236571 created "2016-06-24" @default.
• W2007236571 creator A5005735234 @default.
• W2007236571 creator A5020865656 @default.
• W2007236571 creator A5030863883 @default.
• W2007236571 creator A5033413633 @default.
• W2007236571 creator A5044828294 @default.
• W2007236571 creator A5058254184 @default.
• W2007236571 creator A5060453388 @default.
• W2007236571 creator A5070871031 @default.
• W2007236571 date "2010-02-01" @default.
• W2007236571 modified "2023-09-27" @default.
• W2007236571 title "Alteration of serotonin transporter messenger RNA level in the peripheral blood mononuclear cells from simian/human immunodeficiency virus infected Chinese rhesus macaques (Macaca mulatta)" @default.
• W2007236571 cites W1484692085 @default.
• W2007236571 cites W1907864108 @default.
• W2007236571 cites W1962934739 @default.
• W2007236571 cites W1969044221 @default.
• W2007236571 cites W1971873395 @default.
• W2007236571 cites W1975999093 @default.
• W2007236571 cites W1977282936 @default.
• W2007236571 cites W1985859759 @default.
• W2007236571 cites W1992601070 @default.
• W2007236571 cites W1993725963 @default.
• W2007236571 cites W1997066133 @default.
• W2007236571 cites W2000904449 @default.
• W2007236571 cites W2006858361 @default.
• W2007236571 cites W2007801625 @default.
• W2007236571 cites W2007825914 @default.
• W2007236571 cites W2012129851 @default.
• W2007236571 cites W2013576534 @default.
• W2007236571 cites W2021268946 @default.
• W2007236571 cites W2027398511 @default.
• W2007236571 cites W2030081504 @default.
• W2007236571 cites W2031892008 @default.
• W2007236571 cites W2039268423 @default.
• W2007236571 cites W2044968774 @default.
• W2007236571 cites W2046438298 @default.
• W2007236571 cites W2047201520 @default.
• W2007236571 cites W2049543596 @default.
• W2007236571 cites W2052489119 @default.
• W2007236571 cites W2052602080 @default.
• W2007236571 cites W2057932115 @default.
• W2007236571 cites W2058331407 @default.
• W2007236571 cites W2058976148 @default.
• W2007236571 cites W2061069385 @default.
• W2007236571 cites W2070378956 @default.
• W2007236571 cites W2074341829 @default.
• W2007236571 cites W2074992169 @default.
• W2007236571 cites W2075898931 @default.
• W2007236571 cites W2079507733 @default.
• W2007236571 cites W2080800299 @default.
• W2007236571 cites W2085036778 @default.
• W2007236571 cites W2086311259 @default.
• W2007236571 cites W2097566770 @default.
• W2007236571 cites W2098447911 @default.
• W2007236571 cites W2101106848 @default.
• W2007236571 cites W2103880802 @default.
• W2007236571 cites W2145135755 @default.
• W2007236571 cites W2148457862 @default.
• W2007236571 cites W2156291426 @default.
• W2007236571 cites W2164113824 @default.
• W2007236571 cites W2168279320 @default.
• W2007236571 cites W2171140662 @default.
• W2007236571 cites W4298176974 @default.
• W2007236571 cites W55536439 @default.
• W2007236571 doi "https://doi.org/10.1016/j.bbi.2009.10.008" @default.
• W2007236571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19854262" @default.
• W2007236571 hasPublicationYear "2010" @default.
• W2007236571 type Work @default.
• W2007236571 sameAs 2007236571 @default.
• W2007236571 citedByCount "11" @default.
• W2007236571 countsByYear W20072365712012 @default.
• W2007236571 countsByYear W20072365712013 @default.
• W2007236571 countsByYear W20072365712014 @default.
• W2007236571 countsByYear W20072365712015 @default.
• W2007236571 countsByYear W20072365712016 @default.
• W2007236571 countsByYear W20072365712017 @default.
• W2007236571 countsByYear W20072365712018 @default.
• W2007236571 countsByYear W20072365712019 @default.
• W2007236571 crossrefType "journal-article" @default.
• W2007236571 hasAuthorship W2007236571A5005735234 @default.
• W2007236571 hasAuthorship W2007236571A5020865656 @default.
• W2007236571 hasAuthorship W2007236571A5030863883 @default.
• W2007236571 hasAuthorship W2007236571A5033413633 @default.
• W2007236571 hasAuthorship W2007236571A5044828294 @default.
• W2007236571 hasAuthorship W2007236571A5058254184 @default.
• W2007236571 hasAuthorship W2007236571A5060453388 @default.
• W2007236571 hasAuthorship W2007236571A5070871031 @default.
• W2007236571 hasConcept C104317684 @default.
• W2007236571 hasConcept C135763542 @default.
• W2007236571 hasConcept C137061746 @default.
• W2007236571 hasConcept C159047783 @default.
• W2007236571 hasConcept C202751555 @default.
• W2007236571 hasConcept C203014093 @default.
• W2007236571 hasConcept C2522874641 @default.
• W2007236571 hasConcept C2777995582 @default.
• W2007236571 hasConcept C2778897192 @default.
• W2007236571 hasConcept C2779175743 @default.

• next