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- W2007244580 abstract "Introduction We investigated the effects of acidification and storage on calcium recovery in spot urine samples. Methods In a retrospective study, 43 spot urine samples from patients with metabolic bone disease, which had been previously analysed fresh for calcium and creatinine, were acidified and incubated for 2 h at room temperature and re-analysed. In a prospective study, fresh spot urine samples from 15 volunteers were split into two aliquots - one left unacidified and the other acidified with 6 mol/L HCl to pH< 2. Both aliquots were analysed immediately and after storage at 4°C for 24 h. Results In both studies, the calcium creatinine ratios obtained on acidified and non-acidified spot urine samples were not different, both when measured immediately as well as after storage at 4°C for 24 h. Conclusions The acidification of spot urine samples would thus appear to be unnecessary for calcium/creatinine measurements in metabolic bone disease if they were undertaken within at least 24 h." @default.
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- W2007244580 date "2002-01-01" @default.
- W2007244580 modified "2023-09-27" @default.
- W2007244580 title "Spot urine analysis: acidification does not increase calcium recovery" @default.
- W2007244580 cites W1905630891 @default.
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- W2007244580 doi "https://doi.org/10.1258/0004563021901577" @default.
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