Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007244792> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2007244792 endingPage "320" @default.
- W2007244792 startingPage "313" @default.
- W2007244792 abstract "Binding of Escherichia coli Initiation Factor-1 protein to the nucleic acid lattice induces alterations in the secondary structures of a variety of purine and pyrimidine containing polynucleotides in both the single and double stranded conformations, as assessed by circular dichroism spectroscopy. The helical hairpin form of poly(U), the single-stranded stacked form of poly(C), and the duplex poly(A) · poly(U) (in the presence of Mg2+) are stoichiometrically converted by Initiation Factor-1 (IF-1) to structures spectrally indistinguishable from their partially or completely thermally denatured forms. By contrast, the binding of IF-1 to double stranded poly(C), single- and double-stranded poly(A) elicited spectral responses which were interpreted in terms of diminished base-base interaction, not equivalent to that induced by thermal means. Stoichiometric endpoints of 3–5 nucleotide residuesIF-1 were determined for polynucleotide structures in those cases where light scattering artifacts at low nucleotide residue to protein ratios were absent. In the absence of Mg2+ IF-1 was unable to elicit a conformation alteration effect in poly(A) · poly(U), while for poly(U) much less of an effect was observed than in the presence of this divalent ion. The functional significance of these results is briefly considered." @default.
- W2007244792 created "2016-06-24" @default.
- W2007244792 creator A5021029285 @default.
- W2007244792 creator A5050701853 @default.
- W2007244792 creator A5084819035 @default.
- W2007244792 date "1980-09-01" @default.
- W2007244792 modified "2023-09-27" @default.
- W2007244792 title "A circular dichroism study of Escherichia coli Initiation Factor-1 binding to polynucleotides" @default.
- W2007244792 cites W1550261037 @default.
- W2007244792 cites W1578751920 @default.
- W2007244792 cites W1597213983 @default.
- W2007244792 cites W1597227895 @default.
- W2007244792 cites W1707379481 @default.
- W2007244792 cites W1775749144 @default.
- W2007244792 cites W1806195892 @default.
- W2007244792 cites W1988100456 @default.
- W2007244792 cites W1991645430 @default.
- W2007244792 cites W2008767878 @default.
- W2007244792 cites W2012662523 @default.
- W2007244792 cites W2027518965 @default.
- W2007244792 cites W2040491824 @default.
- W2007244792 cites W2043516348 @default.
- W2007244792 cites W2054028452 @default.
- W2007244792 cites W2055523409 @default.
- W2007244792 cites W2069480622 @default.
- W2007244792 cites W2078961921 @default.
- W2007244792 cites W2085521084 @default.
- W2007244792 cites W4293247451 @default.
- W2007244792 doi "https://doi.org/10.1016/0005-2787(80)90243-9" @default.
- W2007244792 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6996729" @default.
- W2007244792 hasPublicationYear "1980" @default.
- W2007244792 type Work @default.
- W2007244792 sameAs 2007244792 @default.
- W2007244792 citedByCount "13" @default.
- W2007244792 countsByYear W20072447922012 @default.
- W2007244792 countsByYear W20072447922015 @default.
- W2007244792 countsByYear W20072447922022 @default.
- W2007244792 crossrefType "journal-article" @default.
- W2007244792 hasAuthorship W2007244792A5021029285 @default.
- W2007244792 hasAuthorship W2007244792A5050701853 @default.
- W2007244792 hasAuthorship W2007244792A5084819035 @default.
- W2007244792 hasConcept C104317684 @default.
- W2007244792 hasConcept C111921641 @default.
- W2007244792 hasConcept C133571119 @default.
- W2007244792 hasConcept C178790620 @default.
- W2007244792 hasConcept C185592680 @default.
- W2007244792 hasConcept C24107716 @default.
- W2007244792 hasConcept C512185932 @default.
- W2007244792 hasConcept C547475151 @default.
- W2007244792 hasConcept C552990157 @default.
- W2007244792 hasConcept C55493867 @default.
- W2007244792 hasConcept C62614982 @default.
- W2007244792 hasConcept C71240020 @default.
- W2007244792 hasConcept C74884574 @default.
- W2007244792 hasConcept C8010536 @default.
- W2007244792 hasConcept C99611785 @default.
- W2007244792 hasConceptScore W2007244792C104317684 @default.
- W2007244792 hasConceptScore W2007244792C111921641 @default.
- W2007244792 hasConceptScore W2007244792C133571119 @default.
- W2007244792 hasConceptScore W2007244792C178790620 @default.
- W2007244792 hasConceptScore W2007244792C185592680 @default.
- W2007244792 hasConceptScore W2007244792C24107716 @default.
- W2007244792 hasConceptScore W2007244792C512185932 @default.
- W2007244792 hasConceptScore W2007244792C547475151 @default.
- W2007244792 hasConceptScore W2007244792C552990157 @default.
- W2007244792 hasConceptScore W2007244792C55493867 @default.
- W2007244792 hasConceptScore W2007244792C62614982 @default.
- W2007244792 hasConceptScore W2007244792C71240020 @default.
- W2007244792 hasConceptScore W2007244792C74884574 @default.
- W2007244792 hasConceptScore W2007244792C8010536 @default.
- W2007244792 hasConceptScore W2007244792C99611785 @default.
- W2007244792 hasIssue "2" @default.
- W2007244792 hasLocation W20072447921 @default.
- W2007244792 hasLocation W20072447922 @default.
- W2007244792 hasOpenAccess W2007244792 @default.
- W2007244792 hasPrimaryLocation W20072447921 @default.
- W2007244792 hasRelatedWork W1552269101 @default.
- W2007244792 hasRelatedWork W1975122398 @default.
- W2007244792 hasRelatedWork W2032503181 @default.
- W2007244792 hasRelatedWork W2034979205 @default.
- W2007244792 hasRelatedWork W2059177774 @default.
- W2007244792 hasRelatedWork W2082876841 @default.
- W2007244792 hasRelatedWork W2083202085 @default.
- W2007244792 hasRelatedWork W2106218966 @default.
- W2007244792 hasRelatedWork W2124087662 @default.
- W2007244792 hasRelatedWork W2126330691 @default.
- W2007244792 hasVolume "609" @default.
- W2007244792 isParatext "false" @default.
- W2007244792 isRetracted "false" @default.
- W2007244792 magId "2007244792" @default.
- W2007244792 workType "article" @default.