FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007260672> ?p ?o ?g. }

• W2007260672 endingPage "e88420" @default.
• W2007260672 startingPage "e88420" @default.
• W2007260672 abstract "Plasmodium falciparum (Pf) malaria causes 200 million cases worldwide, 8 million being severe and complicated leading to ∼1 million deaths and ∼100,000 abortions annually. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) has been implicated in cytoadherence and infected erythrocyte rosette formation, associated with cerebral malaria; chondroitin sulphate-A attachment and infected erythrocyte sequestration related to pregnancy-associated malaria and other severe forms of disease. An endothelial cell high activity binding peptide is described in several of this ∼300 kDa hypervariable protein’s domains displaying a conserved motif (GACxPxRRxxLC); it established H-bonds with other binding peptides to mediate red blood cell group A and chondroitin sulphate attachment. This motif (when properly modified) induced PfEMP1-specific strain-transcending, fully-protective immunity for the first time in experimental challenge in Aotus monkeys, opening the way forward for a long sought-after vaccine against severe malaria." @default.
• W2007260672 created "2016-06-24" @default.
• W2007260672 creator A5001486791 @default.
• W2007260672 creator A5017366675 @default.
• W2007260672 creator A5019790423 @default.
• W2007260672 creator A5042652382 @default.
• W2007260672 creator A5045376600 @default.
• W2007260672 creator A5048085944 @default.
• W2007260672 date "2014-02-07" @default.
• W2007260672 modified "2023-09-27" @default.
• W2007260672 title "Using the PfEMP1 Head Structure Binding Motif to Deal a Blow at Severe Malaria" @default.
• W2007260672 cites W1417879642 @default.
• W2007260672 cites W1968708504 @default.
• W2007260672 cites W1973978942 @default.
• W2007260672 cites W1980281857 @default.
• W2007260672 cites W1984367265 @default.
• W2007260672 cites W1984522255 @default.
• W2007260672 cites W1985706362 @default.
• W2007260672 cites W1988834631 @default.
• W2007260672 cites W1988988366 @default.
• W2007260672 cites W2003472864 @default.
• W2007260672 cites W2004551743 @default.
• W2007260672 cites W2023722057 @default.
• W2007260672 cites W2042758260 @default.
• W2007260672 cites W2046267069 @default.
• W2007260672 cites W2049700891 @default.
• W2007260672 cites W2052523483 @default.
• W2007260672 cites W2053796585 @default.
• W2007260672 cites W2054512413 @default.
• W2007260672 cites W2062228103 @default.
• W2007260672 cites W2070343769 @default.
• W2007260672 cites W2072975902 @default.
• W2007260672 cites W2074611491 @default.
• W2007260672 cites W2076443493 @default.
• W2007260672 cites W2083442176 @default.
• W2007260672 cites W2083750714 @default.
• W2007260672 cites W2088759544 @default.
• W2007260672 cites W2094545320 @default.
• W2007260672 cites W2094954825 @default.
• W2007260672 cites W2097064355 @default.
• W2007260672 cites W2109289401 @default.
• W2007260672 cites W2115494696 @default.
• W2007260672 cites W2121739093 @default.
• W2007260672 cites W2136302208 @default.
• W2007260672 cites W2148019354 @default.
• W2007260672 cites W2148094373 @default.
• W2007260672 cites W2157038428 @default.
• W2007260672 cites W2949250147 @default.
• W2007260672 doi "https://doi.org/10.1371/journal.pone.0088420" @default.
• W2007260672 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3917906" @default.
• W2007260672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24516657" @default.
• W2007260672 hasPublicationYear "2014" @default.
• W2007260672 type Work @default.
• W2007260672 sameAs 2007260672 @default.
• W2007260672 citedByCount "8" @default.
• W2007260672 countsByYear W20072606722015 @default.
• W2007260672 countsByYear W20072606722016 @default.
• W2007260672 countsByYear W20072606722017 @default.
• W2007260672 countsByYear W20072606722021 @default.
• W2007260672 crossrefType "journal-article" @default.
• W2007260672 hasAuthorship W2007260672A5001486791 @default.
• W2007260672 hasAuthorship W2007260672A5017366675 @default.
• W2007260672 hasAuthorship W2007260672A5019790423 @default.
• W2007260672 hasAuthorship W2007260672A5042652382 @default.
• W2007260672 hasAuthorship W2007260672A5045376600 @default.
• W2007260672 hasAuthorship W2007260672A5048085944 @default.
• W2007260672 hasBestOaLocation W20072606721 @default.
• W2007260672 hasConcept C159047783 @default.
• W2007260672 hasConcept C203014093 @default.
• W2007260672 hasConcept C2776557347 @default.
• W2007260672 hasConcept C2778048844 @default.
• W2007260672 hasConcept C2778371730 @default.
• W2007260672 hasConcept C2908793570 @default.
• W2007260672 hasConcept C86803240 @default.
• W2007260672 hasConcept C95444343 @default.
• W2007260672 hasConceptScore W2007260672C159047783 @default.
• W2007260672 hasConceptScore W2007260672C203014093 @default.
• W2007260672 hasConceptScore W2007260672C2776557347 @default.
• W2007260672 hasConceptScore W2007260672C2778048844 @default.
• W2007260672 hasConceptScore W2007260672C2778371730 @default.
• W2007260672 hasConceptScore W2007260672C2908793570 @default.
• W2007260672 hasConceptScore W2007260672C86803240 @default.
• W2007260672 hasConceptScore W2007260672C95444343 @default.
• W2007260672 hasIssue "2" @default.
• W2007260672 hasLocation W20072606721 @default.
• W2007260672 hasLocation W20072606722 @default.
• W2007260672 hasLocation W20072606723 @default.
• W2007260672 hasLocation W20072606724 @default.
• W2007260672 hasLocation W20072606725 @default.
• W2007260672 hasLocation W20072606726 @default.
• W2007260672 hasOpenAccess W2007260672 @default.
• W2007260672 hasPrimaryLocation W20072606721 @default.
• W2007260672 hasRelatedWork W2000614119 @default.
• W2007260672 hasRelatedWork W2013381485 @default.
• W2007260672 hasRelatedWork W2039976430 @default.
• W2007260672 hasRelatedWork W2055242570 @default.
• W2007260672 hasRelatedWork W2096624589 @default.
• W2007260672 hasRelatedWork W2114807898 @default.

• next