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- W2007260964 abstract "Nasal septal perforations are mainly due to trauma. Our review highlights systemic diseases leading to this disorder.Various systemic diseases may be responsible of nasal septal perforation: Wegener's granulomatosis, systemic lupus erythematosus, antiphospholipid syndrome, sarcoidosis, cryoglobulinaemia. But, very few data are available about the frequency of septum nasal perforation in each disease. Clinical manifestations are numerous and not specific: obstruction, epistaxis, postnasal discharge, whistling, crusting. Asymptomatic forms are frequent. Biopsy of nasal septum is poorly useful for the diagnosis except when granuloma or vasculitis is found. Pathophysiologic mechanisms of nasal septal perforation are ischemic, infectious or inflammatory.Systemic disease may be suspected in unclear nasal septal perforation. More, in systemic disease, even when symptoms are absent, intranasal examination is required." @default.
- W2007260964 created "2016-06-24" @default.
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- W2007260964 date "2002-11-01" @default.
- W2007260964 modified "2023-09-30" @default.
- W2007260964 title "Perforation de la cloison nasale et maladies systémiques" @default.
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- W2007260964 doi "https://doi.org/10.1016/s0248-8663(02)00711-7" @default.
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