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- W2007262203 abstract "Introduction: An employer-based cost-benefit analysis for varenicline versus bupropion was conducted using clinical outcomes from a recently published trial. Methods: A decision tree model was developed based on the net benefit of treatment to produce a nonsmoker at 1 year. Sensitivity analyses were conducted based on quit rates with placebo and varenicline and the cost of varenicline. Results: Estimated 12-month employer cost savings per non-smoking employee were $540.60 for varenicline, $269.80 for bupropion SR generic, $150.80 for bupropion SR brand, and $81.80 for placebo. Varenicline was more cost beneficial than placebo, which had quit rates of 16.9% or less. The quit rate with varenicline would have to be ≤16.9% to lose cost benefit over bupropion SR generic. Conclusions: The economic benefit of varenicline is improved over bupropion, despite the increased initial cost of varenicline." @default.
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- W2007262203 date "2007-04-01" @default.
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- W2007262203 title "An Employer-Based Cost-Benefit Analysis of a Novel Pharmacotherapy Agent for Smoking Cessation" @default.
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- W2007262203 doi "https://doi.org/10.1097/jom.0b013e3180459ff2" @default.
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