Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007272816> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2007272816 endingPage "657" @default.
- W2007272816 startingPage "643" @default.
- W2007272816 abstract "Diphenhydramine, chlorpromazine, and promethazine do not inhibit the initial adjustment of isolated liver mitochondria to hypotonie medium. Chlorpromazine and promethazine in optimum concentrations do inhibit glutathione- or ascorbate-induced swelling-lysis, late isotonic swelling, and a late or second phase of hypotonie swelling. In isotonic medium they do not inhibit electron transport-dependent swelling except in very much greater concentrations, and then only partially. Diphenhydramine does not inhibit glutathione- or ascorbate-induced swelling-lysis, late isotonic swelling, or electron transport-dependent swelling in isotonic medium. In most cases it does inhibit late swelling of mitochondria in hypotonie media. Late swelling of fresh mitochondria in very hypotonie medium may have some relation to electron transport, since it is inhibited by 2, 4-dinitrophenol and most electron transport inhibitors, but late swelling under other circumstances is not. The late swelling of fresh mitochondria in very hypotonic medium, like the late swelling in isotonic medium and most other circumstances, is inhibited by the antioxidant butylated hydroxyanisole, so that lipid peroxidation may be responsible for the changes. With DPHA there is clear indication of a membrane-stabilizing effect independent of electron transport inhibition, uncoupling, or antioxidant activity. With the phenothiazines, the powerful antioxidant action makes it more difficult to determine whether the stabilizing action is direct like that of DPHA or is the result of preventing peroxidation, but they do inhibit swelling in some circumstances when BHA is inactive. The aging of isolated mitochondria results in some membrane change which greatly slows their initial adjustment to hypotonic medium." @default.
- W2007272816 created "2016-06-24" @default.
- W2007272816 creator A5000743985 @default.
- W2007272816 creator A5003422547 @default.
- W2007272816 creator A5032239000 @default.
- W2007272816 creator A5037001217 @default.
- W2007272816 creator A5064752577 @default.
- W2007272816 creator A5079661787 @default.
- W2007272816 date "1964-04-01" @default.
- W2007272816 modified "2023-09-23" @default.
- W2007272816 title "The effect of chlorpromazine, promethazine, and diphenhydramine on swelling of isolated liver mitochondria" @default.
- W2007272816 cites W1556262608 @default.
- W2007272816 cites W1591565299 @default.
- W2007272816 cites W1860329150 @default.
- W2007272816 cites W1971577052 @default.
- W2007272816 cites W2046640569 @default.
- W2007272816 cites W2062941362 @default.
- W2007272816 cites W2068675815 @default.
- W2007272816 cites W2094601956 @default.
- W2007272816 cites W2097103968 @default.
- W2007272816 cites W2309532548 @default.
- W2007272816 cites W2410403194 @default.
- W2007272816 doi "https://doi.org/10.1016/0006-2952(64)90051-6" @default.
- W2007272816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14191871" @default.
- W2007272816 hasPublicationYear "1964" @default.
- W2007272816 type Work @default.
- W2007272816 sameAs 2007272816 @default.
- W2007272816 citedByCount "12" @default.
- W2007272816 crossrefType "journal-article" @default.
- W2007272816 hasAuthorship W2007272816A5000743985 @default.
- W2007272816 hasAuthorship W2007272816A5003422547 @default.
- W2007272816 hasAuthorship W2007272816A5032239000 @default.
- W2007272816 hasAuthorship W2007272816A5037001217 @default.
- W2007272816 hasAuthorship W2007272816A5064752577 @default.
- W2007272816 hasAuthorship W2007272816A5079661787 @default.
- W2007272816 hasConcept C117277713 @default.
- W2007272816 hasConcept C142724271 @default.
- W2007272816 hasConcept C181199279 @default.
- W2007272816 hasConcept C185592680 @default.
- W2007272816 hasConcept C2778004101 @default.
- W2007272816 hasConcept C2778540859 @default.
- W2007272816 hasConcept C2778775820 @default.
- W2007272816 hasConcept C2778794651 @default.
- W2007272816 hasConcept C2780829032 @default.
- W2007272816 hasConcept C28859421 @default.
- W2007272816 hasConcept C538909803 @default.
- W2007272816 hasConcept C55493867 @default.
- W2007272816 hasConcept C57409179 @default.
- W2007272816 hasConcept C71924100 @default.
- W2007272816 hasConcept C86803240 @default.
- W2007272816 hasConcept C98274493 @default.
- W2007272816 hasConceptScore W2007272816C117277713 @default.
- W2007272816 hasConceptScore W2007272816C142724271 @default.
- W2007272816 hasConceptScore W2007272816C181199279 @default.
- W2007272816 hasConceptScore W2007272816C185592680 @default.
- W2007272816 hasConceptScore W2007272816C2778004101 @default.
- W2007272816 hasConceptScore W2007272816C2778540859 @default.
- W2007272816 hasConceptScore W2007272816C2778775820 @default.
- W2007272816 hasConceptScore W2007272816C2778794651 @default.
- W2007272816 hasConceptScore W2007272816C2780829032 @default.
- W2007272816 hasConceptScore W2007272816C28859421 @default.
- W2007272816 hasConceptScore W2007272816C538909803 @default.
- W2007272816 hasConceptScore W2007272816C55493867 @default.
- W2007272816 hasConceptScore W2007272816C57409179 @default.
- W2007272816 hasConceptScore W2007272816C71924100 @default.
- W2007272816 hasConceptScore W2007272816C86803240 @default.
- W2007272816 hasConceptScore W2007272816C98274493 @default.
- W2007272816 hasIssue "4" @default.
- W2007272816 hasLocation W20072728161 @default.
- W2007272816 hasLocation W20072728162 @default.
- W2007272816 hasOpenAccess W2007272816 @default.
- W2007272816 hasPrimaryLocation W20072728161 @default.
- W2007272816 hasRelatedWork W195608723 @default.
- W2007272816 hasRelatedWork W2007272816 @default.
- W2007272816 hasRelatedWork W2016386292 @default.
- W2007272816 hasRelatedWork W2019344027 @default.
- W2007272816 hasRelatedWork W2054476893 @default.
- W2007272816 hasRelatedWork W2060906860 @default.
- W2007272816 hasRelatedWork W2065982502 @default.
- W2007272816 hasRelatedWork W2092544241 @default.
- W2007272816 hasRelatedWork W2382552609 @default.
- W2007272816 hasRelatedWork W38819264 @default.
- W2007272816 hasVolume "13" @default.
- W2007272816 isParatext "false" @default.
- W2007272816 isRetracted "false" @default.
- W2007272816 magId "2007272816" @default.
- W2007272816 workType "article" @default.