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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007273003> ?p ?o ?g. }

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• W2007273003 abstract "Immunosenescence is an age-associated dysregulation of immune function which may contribute to the increased susceptibility of the elderly to infectious disease. Although age-associated changes are measurable in the innate immune system, it is the adaptive arm of the immune system which is particularly susceptible to the deleterious effects of ageing, especially the T cell compartment. In this review, the characteristics of longitudinal ageing in cultured monoclonal human T cell populations will be summarized. It will be argued that parallels between this in vitro model and T cell senescence in vivo suggest the use of such models to screen for interventions ameliorating immunosenescence in vivo." @default.
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• W2007273003 date "2000-02-01" @default.
• W2007273003 modified "2023-09-30" @default.
• W2007273003 title "In vitro senescence models for human T lymphocytes" @default.
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• W2007273003 doi "https://doi.org/10.1016/s0264-410x(99)00504-6" @default.
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