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• W2007276563 abstract "Sarcomas are distinctly heterogeneous tumors and a variety of subtypes have been described. Although several diagnostic explorations in the past three decades, such as identification of chromosomal translocation, have greatly improved the diagnosis of soft tissue sarcomas, the unsolved issues, including the limited useful biomarkers, remain. Emerging reports on miRNAs in soft tissue sarcomas have provided clues to solving these problems. Evidence of circulating miRNAs in patients with soft tissue sarcomas and healthy individuals has been accumulated and is accelerating their potential to develop into clinical applications. Moreover, miRNAs that function as novel prognostic factors have been identified, thereby facilitating their use in miRNA-targeted therapy. In this review, we provide an overview of the current knowledge on miRNA deregulation in soft tissue sarcomas, and discuss their potential as novel biomarkers and therapeutics." @default.
• W2007276563 created "2016-06-24" @default.
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• W2007276563 creator A5020130249 @default.
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• W2007276563 creator A5055554576 @default.
• W2007276563 creator A5060788429 @default.
• W2007276563 creator A5065384314 @default.
• W2007276563 date "2014-01-01" @default.
• W2007276563 modified "2023-10-03" @default.
• W2007276563 title "MicroRNAs in Soft Tissue Sarcomas: Overview of the Accumulating Evidence and Importance as Novel Biomarkers" @default.
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