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- W2007279969 abstract "Adaptive-rate pacemakers are designed to restore appropriate heart rates for patients during daily life. Wilkoff describes a linear relationship between heart rate reserve and workload reserve. This clinical study investigated whether appropriate rate response can be achieved using an automatic algorithm. 15 patients received a pacemaker (INSIGNIA Ultra, Guidant Corporation) using a blend of ventilation and activity sensors. The Minute Ventilation Response Factor was automatically determined using an algorithm (AutoLifestyle™) that records the patient's maximum ventilation over time and adjusts the response factor per the patient actual ventilation. The patient age was the only required variable. After 1 month a symptom limited exercise test (CAEP protocol) was performed and the adaptive response was evaluated. The slope of the heart rate reserve to workload reserve averaged 0.87 (range 0.3-1.3, median 0.88, standard deviation .28). The slope of 67% of patients (10 of 15) fell within the normal confidence intervals. The slope of the remaining patients fell below the normal confidence intervals. AutoLifestyle™ can provide appropriate restoration of chronotropic response without extensive testing." @default.
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- W2007279969 date "2005-10-01" @default.
- W2007279969 modified "2023-10-06" @default.
- W2007279969 title "Automatic Adjustment of the Response Factor Approaching Physiology" @default.
- W2007279969 doi "https://doi.org/10.1016/j.eupc.2005.08.056" @default.
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