Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007284305> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2007284305 endingPage "550" @default.
- W2007284305 startingPage "537" @default.
- W2007284305 abstract "Inversion, the process by which Volvox embryos turn inside out, was analyzed by a combination of geometrical and experimental techniques. It was shown that simple geometric figures are adequate to represent cell shapes during inversion and that cell volumes remain constant as cell shapes change and the embryo inverts. The first stage of inversion, phialopore opening, results from the release of compressive forces as the embryo withdraws from its surrounding vesicle during a two-stage contraction of each cell around its radial axis. Premature phialopore opening occurs when withdrawal of the embryo from the vesicle is elicited artificially by exposure to either calcium ionophore or hypertonic solutions. The major event of inversion, generation of negative curvature, requires both microtubule-driven elongation of cells (to produce a classical “flask” shape) and cytochalasin-sensitive active migration of cytoplasmic bridges to the outermost ends of flask cells. Colchicine, cyclic GMP and isobutyl methyl xanthine (individually) block both normal elongation and bridge migration; cytochalasin D blocks bridge migration selectively. Flask cell formation and bridge migration are adequate to account for the negative curvature observed. An asymmetric bending of flask cell stalks along the ring of maximum curvature accounts for the fact that the embryo is not constricted in a “purse-string” fashion as negative curvature is generated. Inversion of the posterior hemisphere involves an elastic snap-through resulting from a combination of compressive stresses generated by inversion of the anterior hemisphere and the circumferential restraint imposed by cells at the equator. We conclude that the observed changes in cell shape and the migration of cytoplasmic bridges are the result of an ordered process of membrane-cytoskeletal interactions, and both necessary and sufficient to account for the morphogenetic process of inversion in Volvox." @default.
- W2007284305 created "2016-06-24" @default.
- W2007284305 creator A5008056610 @default.
- W2007284305 creator A5061357549 @default.
- W2007284305 creator A5064058433 @default.
- W2007284305 date "1979-07-01" @default.
- W2007284305 modified "2023-10-14" @default.
- W2007284305 title "Morphogenesis in volvox: Analysis of critical variables" @default.
- W2007284305 cites W1556559416 @default.
- W2007284305 cites W1576609943 @default.
- W2007284305 cites W1772236019 @default.
- W2007284305 cites W1971057523 @default.
- W2007284305 cites W1983970144 @default.
- W2007284305 cites W2026261647 @default.
- W2007284305 cites W2035751194 @default.
- W2007284305 cites W2072060454 @default.
- W2007284305 cites W2073192482 @default.
- W2007284305 cites W2073214979 @default.
- W2007284305 cites W2079174494 @default.
- W2007284305 cites W2087155996 @default.
- W2007284305 cites W2089271787 @default.
- W2007284305 cites W2138014752 @default.
- W2007284305 cites W2150267107 @default.
- W2007284305 cites W2765493213 @default.
- W2007284305 doi "https://doi.org/10.1016/0092-8674(79)90262-9" @default.
- W2007284305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/476832" @default.
- W2007284305 hasPublicationYear "1979" @default.
- W2007284305 type Work @default.
- W2007284305 sameAs 2007284305 @default.
- W2007284305 citedByCount "67" @default.
- W2007284305 countsByYear W20072843052012 @default.
- W2007284305 countsByYear W20072843052013 @default.
- W2007284305 countsByYear W20072843052015 @default.
- W2007284305 countsByYear W20072843052016 @default.
- W2007284305 countsByYear W20072843052017 @default.
- W2007284305 countsByYear W20072843052018 @default.
- W2007284305 countsByYear W20072843052019 @default.
- W2007284305 countsByYear W20072843052020 @default.
- W2007284305 countsByYear W20072843052023 @default.
- W2007284305 crossrefType "journal-article" @default.
- W2007284305 hasAuthorship W2007284305A5008056610 @default.
- W2007284305 hasAuthorship W2007284305A5061357549 @default.
- W2007284305 hasAuthorship W2007284305A5064058433 @default.
- W2007284305 hasConcept C104317684 @default.
- W2007284305 hasConcept C105702510 @default.
- W2007284305 hasConcept C12554922 @default.
- W2007284305 hasConcept C130316041 @default.
- W2007284305 hasConcept C1491633281 @default.
- W2007284305 hasConcept C195065555 @default.
- W2007284305 hasConcept C2524010 @default.
- W2007284305 hasConcept C2779012151 @default.
- W2007284305 hasConcept C33923547 @default.
- W2007284305 hasConcept C40692019 @default.
- W2007284305 hasConcept C41625074 @default.
- W2007284305 hasConcept C55493867 @default.
- W2007284305 hasConcept C86803240 @default.
- W2007284305 hasConcept C95444343 @default.
- W2007284305 hasConceptScore W2007284305C104317684 @default.
- W2007284305 hasConceptScore W2007284305C105702510 @default.
- W2007284305 hasConceptScore W2007284305C12554922 @default.
- W2007284305 hasConceptScore W2007284305C130316041 @default.
- W2007284305 hasConceptScore W2007284305C1491633281 @default.
- W2007284305 hasConceptScore W2007284305C195065555 @default.
- W2007284305 hasConceptScore W2007284305C2524010 @default.
- W2007284305 hasConceptScore W2007284305C2779012151 @default.
- W2007284305 hasConceptScore W2007284305C33923547 @default.
- W2007284305 hasConceptScore W2007284305C40692019 @default.
- W2007284305 hasConceptScore W2007284305C41625074 @default.
- W2007284305 hasConceptScore W2007284305C55493867 @default.
- W2007284305 hasConceptScore W2007284305C86803240 @default.
- W2007284305 hasConceptScore W2007284305C95444343 @default.
- W2007284305 hasIssue "3" @default.
- W2007284305 hasLocation W20072843051 @default.
- W2007284305 hasLocation W20072843052 @default.
- W2007284305 hasOpenAccess W2007284305 @default.
- W2007284305 hasPrimaryLocation W20072843051 @default.
- W2007284305 hasRelatedWork W2047459759 @default.
- W2007284305 hasRelatedWork W2060453216 @default.
- W2007284305 hasRelatedWork W2140755714 @default.
- W2007284305 hasRelatedWork W2160135126 @default.
- W2007284305 hasRelatedWork W2181515674 @default.
- W2007284305 hasRelatedWork W2588855213 @default.
- W2007284305 hasRelatedWork W2768562379 @default.
- W2007284305 hasRelatedWork W4233852699 @default.
- W2007284305 hasRelatedWork W4237599183 @default.
- W2007284305 hasRelatedWork W4244871640 @default.
- W2007284305 hasVolume "17" @default.
- W2007284305 isParatext "false" @default.
- W2007284305 isRetracted "false" @default.
- W2007284305 magId "2007284305" @default.
- W2007284305 workType "article" @default.