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• W2007289350 startingPage "E171" @default.
• W2007289350 abstract "The T-cell response defines the pathogenesis of many common chronic disease states, including diabetes, rheumatoid arthritis, and transplant rejection. Therefore, a diagnostic strategy that visualizes this response can potentially lead to early therapeutic intervention, avoiding catastrophic organ failure or prolonged sickness. In addition, the means to deliver a drug dose to those cells in situ with the same specificity used to image those cells would provide for a powerful therapeutic alternative for many disease states involving T cells. In this report, we review emerging nanosystems that can be used for simultaneous tracking and drug delivery to those cells. Because of their versatility, these systems—which combine specific receptor targeting with an imaging agent and drug delivery—are suited to both basic science and applications, from developing therapeutic strategies for autoimmune and alloimmune diseases, to noninvasive tracking of pathogenic T-cell migration." @default.
• W2007289350 created "2016-06-24" @default.
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• W2007289350 creator A5052296033 @default.
• W2007289350 date "2007-06-01" @default.
• W2007289350 modified "2023-10-16" @default.
• W2007289350 title "Nanosystems for simultaneous imaging and drug delivery to T cells" @default.
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